The CD4 percentage (CD4%) is the percentage of white blood cells (lymphocytes) that are CD4 cells.
The immune system contains lots of different cells. The two main types of lymphocytes are T cells and B cells. CD4 cells are a type of T cell. So the CD4% looks at the CD4 count in relation to other immune cells.
CD4% is sometimes a more stable indication of whether there has been a change in the immune system. If the percentage hasn’t changed the change in the absolute count is not important.
The normal range for HIV-negative adults is 30% to 60%; people with HIV often have a lower percentage. A percentage below 14% indicates an AIDS diagnosis. CD4 percentage, rather than CD4 count, is used to monitor disease progression in children.
CD4% is sometimes a more stable indication of whether there has been a change in the immune system. If the percentage hasn’t changed the change in the absolute count is not important.
- A CD4% of 12-15% is about the same as a count of under 200 cells/mm3.
- A CD4% of 29% is about the same as a count of over 500 cells/mm3, but there is a wider range for higher values.
- The average normal CD4 percentage for someone who is HIV negative is about 40%. The normal range is anywhere from about 25% to 65%.
The CD4% count is also used to monitor children under 12 years old. This is because babies are born with very high CD4 levels. A baby can have a CD4 count that is 3000 cells/mm3.
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Elevated levels of "% CD 4 Pos. Lymph." in a T + B-Lymphocyte Differential panel can signify an increase in CD4 positive T-cells in the blood. High CD4 counts might occur in situations such as immune system recovery following treatment for conditions like HIV/AIDS, or in response to certain infections where the body is actively fighting off pathogens. They can also be seen in some autoimmune disorders, where the immune system is overactive. However, it's important to consider these results in the context of other clinical findings and the overall health status of the individual. For precise interpretation, consultation with healthcare professionals is advised.
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I have been using Healthmatters.io since 2021. I travel all over the world and use different doctors and health facilities. This site has allowed me to consolidate all my various test results over 14 years in one place. And every doctor that I show this to has been impressed. Because with any health professional I talk to, I can pull up historical results in seconds. It is invaluable. Even going back to the same doctor, they usually do not have the historical results from their facility in a graph format. That has been very helpful.
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Low levels of "% CD 4 Pos. Lymph." in a T + B-Lymphocyte Differential panel can indicate a decreased count of CD4 positive T-cells, which are crucial for a healthy immune response. This reduction is commonly associated with HIV/AIDS, where the virus targets these cells, leading to their depletion. Other possible causes for low CD4 cell counts include certain types of cancer, such as lymphoma, autoimmune diseases, or the use of immunosuppressive drugs. Low CD4 counts can result in a weakened immune system, making the body more susceptible to infections and diseases. It's important to interpret these levels in the context of overall health and related medical tests.
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Anthony
Unlimited Plan Member since 2021
I have been using Healthmatters.io since 2021. I travel all over the world and use different doctors and health facilities. This site has allowed me to consolidate all my various test results over 14 years in one place. And every doctor that I show this to has been impressed. Because with any health professional I talk to, I can pull up historical results in seconds. It is invaluable. Even going back to the same doctor, they usually do not have the historical results from their facility in a graph format. That has been very helpful.
Karin
Advanced Plan Member since 2020
What fantastic service and great, easy-to-follow layouts! I love your website; it makes it so helpful to see patterns in my health data. It's truly a pleasure to use. I only wish the NHS was as organized and quick as Healthmatters.io. You've set a new standard for health tracking!
Paul
Healthmatters Pro Member since 2024
As a PRO member and medical practitioner, Healthmatters.io has been an invaluable tool for tracking my clients' data. The layout is intuitive, making it easy to monitor trends and spot patterns over time. The ability to customize reports and charts helps me present information clearly to my clients, improving communication and outcomes. It's streamlined my workflow, saving me time and providing insights at a glance. Highly recommended for any practitioner looking for a comprehensive and user-friendly solution to track patient labs!
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