Calculated Total (E+NE)

Optimal Result: 30 - 130 mcg/g Cr.

In a Catecholamines, Fractionated, Random Urine test, "Calculated Total (E+NE)" typically refers to the calculated total concentration of epinephrine (E) and norepinephrine (NE) in the urine sample.

Epinephrine (also known as adrenaline) and norepinephrine (noradrenaline) are two of the main catecholamines measured in this type of test. These hormones are produced by the adrenal glands and play essential roles in the body's response to stress and the "fight or flight" response.

To calculate the total concentration of epinephrine and norepinephrine, the laboratory adds together the individual measurements of these two catecholamines found in the urine sample. The result is reported in units such as micrograms per gram of creatinine (μg/g Cr) or picograms per milliliter (pg/mL), depending on the laboratory's standard units of measurement.

This calculated total provides a more comprehensive assessment of the overall catecholamine levels in the urine and can be useful in diagnosing conditions related to catecholamine excess or dysfunction, such as pheochromocytoma or paraganglioma.

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