Alternaria Toxin (Alternariol) - IgG

Serum
Optimal Result: 0 - 0.15 Units.

Alternaria Toxin is cytotoxic (toxic to cells), mutagenic (causes mutations), genotoxic (genes), and causes immune suppression. This mycotoxin is also known to form reactive oxygen species (ROS) and to lower testosterone.

Alternaria alternata is one of the most common fungi associated with asthma.

Not only the presence of asthma but also persistence and severity of asthma have been strongly associated with sensitization and exposure to A alternata. Although exposure to Alternaria is an important risk factor for asthma, few studies have assessed exposure to this fungus in indoor environments.

A alternata, a cosmopolitan saprophyte commonly found in soil and plants, is usually considered an outdoor allergen.

Although most intense exposure is likely to occur outdoors, Alternariaand other allergenic fungi are also found in indoor environments.

References:

- Exposure to Alternaria alternata in US homes is associated with asthma symptoms (link)

What does it mean if your Alternaria Toxin (Alternariol) - IgG result is too high?

Exposure to A alternata in US homes is associated with active asthma symptoms.

Alternaria alternata is one of the most common fungi associated with asthma. Not only the presence of asthma but also persistence and severity of asthma have been strongly associated with sensitization and exposure to A alternata. Although exposure to Alternaria is an important risk factor for asthma, few studies have assessed exposure to this fungus in indoor environments.

A alternata, a cosmopolitan saprophyte commonly found in soil and plants, is usually considered an outdoor allergen. Although most intense exposure is likely to occur outdoors, Alternaria and other allergenic fungi are also found in indoor environments. Yet fungal allergen exposures in indoor environments have not been characterized as well as other indoor allergens (eg, house dust mite, cockroach, and pet allergens). [L]

An allergist/immunologist and/or a pulmonologist should be consulted for the diagnosis and long-term follow-up care for any conditions related to mold allergy. An allergist/immunologist can offer advice on how to avoid allergens and may perform skin tests or initiate a course of immunotherapy in people with allergic rhinitis or conjunctivitis if clinically indicated.

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