Succinic Acid

Possible causes:

• Impaired metabolism due to low cofactors (Fe, B2)
• Bacterial degradation of glutamine
• Dysbiosis (=microbial imbalance or maladaptation on or inside the body, such as an impaired microbiota.)
• UTI (=urinary tract infection. UTI is an infection in any part of your urinary system, your kidneys, ureters, bladder and urethra. Most infections involve the lower urinary tract — the bladder and the urethra.)

Deficiencies of Fe (=Iron) or B2 (=Riboflavin) or Coenzyme Q10. Clinical signs of CoQ10 and Riboflavin deficiencies include fatigue, lassitude (=lack of energy) and myocardial and neurological degeneration. CoQ10 depletion can be tissue specific.

Additional investigations:

• Vitamins & Minerals analysis
• Urinary Amino Acids test
• Investigate possible causes of malabsorption, dysbiosis or UTI
• Intestinal permeability test
• IgG food sensitivity test
• Comprehensive digestive stool analysis
• Functional liver detoxification profile

Treatment considerations:

• Mucosal support
• Correct malabsorption, dysbiosis or UTI
• Elimination diet
• Supplement Fe or B2 if low

Low succinic acid can be due to excess aluminum in your system. Low levels may indicate the need for leucine / isoleucine supplementation.

Succinate (or succinic acid) is an important metabolite that is involved in several chemical processes in the body.