Pathogen-Associated Immune Reactivity Screen (Cyrex Laboratories)

Streptococcal M Protein

Optimal Result: 0.1 - 1.4 ELISA Index.

M Protein is an extracellular product of Streptococcus that contributes to the pathogenicity of the gram-positive bacterium. Antibody response against streptococcal M protein and its reaction with myosin may result in endothelial cell damage and the release of inner valve proteins. This results in antibody production against collagen, vimentin, elastin and laminin, which may contribute to the pathogenesis of streptococcal-associated disorders.

What does it mean if your Streptococcal M Protein result is too high?

Increased risk of neurological disorders including obsessive compulsive disorder (OCD), pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS), rheumatic heart disorders and reactive arthritis.

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