The SARS-CoV-2 IgG assay is intended for qualitative and semi-quantitative detection of IgG antibodies to the S1 receptor binding domain (RBD) of the SARS-CoV-2 spike protein. The measurement of IgG levels can provide insight to an individual's adaptive immune response to a SARS-CoV-2 infection or vaccination. Although the assay is designed to assess the level of an individual's immune response, studies are still needed to determine the index level threshold that confers protective immunity as well as how long the adaptive immune response may last post-infection or via vaccination.
What is an antibody?
An antibody (also known as an immunoglobulin) is part of our body’s response to a foreign molecule or pathogen (also known as an antigen) such as a virus or bacterium. The immune response is valuable as it helps to fight off infection. Protective antibodies can in some cases provide long-term immunity, so we do not become re-infected with the same viruses or bacteria. As such, antibodies are vital for our health.
Yet, we don’t always develop antibodies—or the right or sufficient antibodies—to fight off all infectious diseases. For example, people infected with HIV or hepatitis C virus do not usually develop protective antibodies.
There are five primary classes of antibodies. Of those, IgG, IgM, and IgA are often used as part of infectious disease serology testing.
- IgG antibodies are found in all body fluids. They account for 75 to 80 % of all antibodies. IgG antibodies are very important in fighting bacterial and viral infections and when present indicate that someone has previously been exposed to a particular antigen and has developed an immune response. In general, these antibodies usually appear 10-14 days after symptom onset.
- IgM antibodies are found in blood and lymph fluid and are the first type of antibody made in response to an infection, usually detectable within 3-7 days from the start of the infection.
- IgA antibodies play a crucial role in the immune function of mucous membranes, such as the respiratory epithelium, but is also found in the blood. These antibodies also appear early in the infection process (3-7 days).
Antibody testing provides insight into an individual’s immune response after exposure to the SARS-CoV-2 virus but is not intended to diagnose an active infection. For those vaccinated, the measurement of IgG levels can be used to assess whether an individual has mounted an immune response to the COVID-19 vaccine. Although this test is designed to provide information on one’s immune response, studies are still needed to determine the level that indicates protective immunity as well as how long the immune response may last.
Important note:
This test should not be used to diagnose or exclude an acute SARS-CoV-2 infection. If acute infection is suspected, direct testing by molecular methods for SARS-CoV-2 is necessary. False positive results for the test may occur due to cross-reactivity from pre-existing antibodies or other possible causes.
Keeping track of your medical data and laboratory results while understanding what they mean empowers positive health outcomes.
Keeping track of your medical data and lab results while understanding what they mean empowers positive health outcomes.
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A positive IgG antibody test result suggests recent or prior infection with SARS-CoV-2. It usually takes at least 10 days after symptom onset for IgG detectable levels to be reached. Patients tested prior to this time may be negative for SARS-CoV-2 IgG antibodies. An IgG positive result may suggest an immune response to a primary infection with SARS-CoV-2 or to a COVID-19 vaccination, but the relationship between IgG positivity and immunity to SARS-CoV-2 has not yet been firmly established. At this time, a positive IgG result has not been shown to indicate immunity or prevent transmission of COVID-19, as such social distancing, also called “physical distancing,” should still be followed to assure that we continue to protect ourselves, our family, and our community.
If you have IgG antibodies and you have symptoms, you likely have an active infection, you may infect others, and you may need to seek medical attention.
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Unlock Your Health Journey with Healthmatters.io! Ever wished for a one-stop digital health haven for all your lab tests? Look no further! Healthmatters.io is your personalized health dashboard, bringing together test reports from any lab. Say goodbye to scattered results—organize and centralize your lab data effortlessly. Dive into the details of each biomarker and gain insights into the meaning behind your medical test data.
Join the community of thousands who've transformed the way they understand their lab results. Experience the joy of having all your lab data neatly organized, regardless of where or when the tests were done.
For our professional users, Healthmatters.io is a game-changer. Revel in the intuitive tools that not only streamline analysis but also save valuable time when delving into your client's lab report history. It's not just a dashboard; it's your gateway to a smarter, more informed health journey!
Healthmatters.io personal account provides in-depth research on 4000+ biomarkers, including information and suggestions for test panels such as, but not limited to:
You can combine all test reports inside your Healthmatters account and keep them in one place. It gives you an excellent overview of all your health data. Once you retest, you can add new results and compare them.
If you are still determining whether Healthmatters support your lab results, the rule is that if you can test it, you can upload it to Healthmatters.
While we do talk about popular labs, we welcome reports from lots of other places too. It's as simple as this: if you can get a test done, you can upload it to Healthmatters. We can interpret results from any lab out there. If laboratories can analyze it, we can interpret it.
Still on the hunt for a specific biomarker? Just tell us, and we'll add it to our database. Anything from blood, urine, saliva, or stool can be uploaded, understood, and tracked with your Healthmatters account!
There are two ways to add your test reports to your healthmatters.io account. One option is to input the data using the data entry forms. The other method is to utilize our "Data entry service."
Our data entry forms offer an easy, fast, and free way for you to input the reports yourself. Self-entry allows you to add an unlimited number of reports at no cost. We make the self-entry process user-friendly, providing dozens of templates that pre-populate the most popular laboratory panels and offering instant feedback on entered values.
For those who prefer assistance, we offer a "Data entry service" to help you input your data. Simply attach an image or file of your lab test results, and a qualified team member from our data entry team will add the results for you. We support various file types, including PDFs, JPGs, or Excel. This service is particularly useful if you have many reports to upload or if you're too busy to handle the data entry yourself.
Our special data entry service makes it easy to add your results to your private dashboard. Just attach an image or a file of your lab test results, and our skilled data entry team will do the work for you. It's all done by humans, ensuring that your data is entered accurately and with personal care for each client.
Depending on your account, the data entry service can be included for free or come at an additional cost of $15 per report.
For users on the Complete monthly plan, the first report is entered free of charge, and each additional report incurs a fee of $15.
Unlimited account holders enjoy the entry of ten reports without charge. Subsequent reports are subject to a $15 fee per report.
Additionally, users on the Complete plan can upgrade to a yearly subscription from the account settings. The annual subscription includes a data entry service for five reports.
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Additionally, you can upgrade to the yearly Advanced plan from within your account. The annual cost is $79, and it comes with a data entry service for five reports.
You can always upgrade to a lifetime version with a prorated price from a monthly or yearly subscription.
Simply log in and navigate to your account settings to cancel your subscription. Scroll down to locate the 'Cancel' button at the bottom of the page. Ensure you cancel at least one day before the renewal date to prevent any charges. Once cancellation is requested, the subscription remains active until the conclusion of the current billing cycle.
Unlocking the insights from your lab tests has never been this intuitive! We've crafted multiple ways for you to navigate your data, whether you're glancing at a single report or delving into a treasure trove of testing data.
1. Graph View:Dive into a visual journey with our biomarker graphs, showcasing over 40 data points. Combining years of results unveils trends, empowering you to make informed decisions. Our visualization tools make it a breeze to compare and understand changes over time, even if your results are from different labs. A search function and filters simplify the exploration of extensive data, allowing you to focus on what needs attention.
2. All Tests ViewGet a quick grasp of your test reports in minutes! Explore neatly organized reports on a timeline, highlighting crucial details like dates, critical results, and lab/panel names. Each report opens up to reveal in-depth descriptions and additional recommendations for each biomarker. The history of previous results is just a click away, and you can download a comprehensive report for deeper insights. Color-coded and user-friendly, it's designed for easy reading, understanding, and navigation.
3. Table View:For a holistic view of all biomarkers side by side, our table view is your go-to. Results are neatly displayed in a categorized and dated table, ideal for those with an extensive test history. Utilize sorting, filters, and color-coding to enhance your analysis and gain extra insights.
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Yes, you can download information from your account. We can compile your labs into a CSV file. To download all your labs, you can go to Account Settings, and at the bottom of the page, you will find a link to download your information.
Yes, you can print your report. To do so, navigate to "All tests" and open the report you wish to print. You'll find a print button in the right corner of the report. Click on it, and your browser's print window will open. If you prefer to print in a bigger typeface, adjust the scale using the print window settings.
A personal account is all about keeping your own lab test results in check. It's just for you and your personal use.
The professional or business account is designed for health professionals who wish to track and organize their clients' laboratory results.
To learn more about Healthmatters Pro, please refer to the professional page.
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