Rotavirus IgA+IgM

Optimal result: 0.1 – 1.9 ELISA Index

The detection of salivary antibodies to Rotavirus in an infant may indicate either mucosal immune protection in the absence of diarrhea, or if accompanied by diarrhea, current/recent onset Rotavirus infection.

In adults, elevated salivary antibody production to Rotavirus has been shown to indicate active or recent infection.

In one study of injected adults, antibodies rose four-fold after 13 days and then decreased significantly by 27 days after injection of the virus. Hjelt and colleagues found that secretory immunoglobulins could persist even after one month of naturally-occurring infection in children and in some subjects, elevated antibodies were found several months later.

Human rotaviruses belong to the family of Reoviridae. Rotavirus is a double-stranded RNA virus that is commonly associated with gastroenteritis in children.

Known Cross-Reactions: Pollen allergen of Parietaria

Human rotaviruses belong to the family of Reoviridae. Rotavirus is a double-stranded RNA virus that is commonly associated with gastroenteritis in children.

Known Cross-Reactions: Pollen allergen of Parietaria

References:

Aiyar, et al. Rotavirus-specific antibody response in saliva of infants with rotavirus diarrhea. J Infect Dis, 1990; 162:1383-1384.

Di Somma, et al. Cross-reactivity between the major Parietaria allergen and rotavirus VP4 protein. Allergy, 2003; 58(6):503-510.

Hjelt, et al. Antibody response in serum and intestine in children up to six months after a naturally acquired rotavirus gastroenteritis. J Pediatr Gastroenterol Nutr, 1986; 5:74-80.

Mestecky and McGhee. Immunoglobulin A (IgA): molecular and cellular interactions involved in IgA biosynthesis and immune response. Adv Immunol, l987; 40:153-245.

Molyneaux. Human immunity to rotavirus. Med Microbiol, 1995; 43:397-404.

Ward, et al. Salivary antibody titers in adults challenged with a human rotavirus. Med Virol, 1992; 36:222-225.

Rotavirus IgA+IgM
Healthmatters dashboard showing biomarker trend graph

Every lab result you’ve ever had, charted and explained.

Healthmatters is a tracker for your lab results. Upload a report from any lab, any country — every marker charted and explained.

Start with my report →
Beyond Rotavirus IgA+IgM — 10,000+ markers explained
One Rotavirus IgA+IgM result tells you where you are. Your history tells you where you’re heading. Upload your past lab reports and see this marker — and every marker on them —every marker charted against your own lab’s ranges.
Start with this report →
Healthmatters timeline preview showing biomarker trends over time
Clinical Sources & References

All our content is backed by peer-reviewed studies, academic research, and trusted medical sources. We’re committed to accuracy and transparency — see our editorial policy for details.

Article Review Log
Written by Healthmatters Editorial Team
Healthmatters Lifetime Plan

Pay $250. Track your health forever

One payment. No renewals. Yours for life.

10,000+ biomarkers explained · trends over time

See other plans →
Secure checkout via Stripe · GDPR & HIPAA
We accept results from any lab
LabCorp Quest Diagnostics Genova Diagnostics DUTCH Test Doctor's Data Vibrant America ZRT Laboratory Cyrex Labs + any other lab

What members are saying

★★★★★ 10,000+ happy members
★★★★★

"Watching my numbers move over the years — instead of forgetting last time's results — completely changed how I manage my health."

Daniel
Member since 2022
★★★★★

"Living across several countries made keeping my lab results organized a real challenge. Healthmatters brought my results from the USA, Spain, and Germany together — 20 years of history, with long-term trends instead of scattered reports."

Ben
Member since 2021 · tracks across countries
★★★★★

"Standard lab ranges are too wide for how I practice — 'normal' isn't optimal. I set my own bands, so a client sees yellow before a marker goes officially out of range. That's the conversation I want to be having."

Dr. Alexandra
Functional medicine · 6 yrs on Pro