Ratio: Norepi/Epi

Optimal Result: 5.2 - 13.7 µg/g creatinine.

ZRT Laboratory (Urinary Neurotransmitters) ZRT Laboratory

From Healthmatters.io Team

Lab Results Explained and Tracked

Epinephrine and norepinephrine are two neurotransmitters that also serve as hormones, and they belong to a class of compounds known as catecholamines. As hormones, they influence different parts of your body and stimulate your central nervous system. Having too much or too little of either of them can have noticeable effects on your health.

Both epinephrine and norepinephrine can affect your heart, blood sugar levels, and blood vessels. However, norepinephrine can also make your blood vessels become narrower, increasing blood pressure.

Epinephrine, also called adrenaline, has powerful effects on the body. These include:

- increased blood sugar levels

- increased heart rate

- increased contractility (how hard the heart squeezes)

- relaxation of smooth muscle in the airways to improve breathing

Norepinephrine, also called noradrenaline, has effects similar to those of epinephrine, such as:

- increased blood sugar levels

- increased heart rate

- increased contractility

Norepinephrine can also cause your blood vessels to narrow, which increases blood pressure.

Lab Results Explained and Tracked

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What does it mean if your Ratio: Norepi/Epi result is too high?

Elevated Ratio: Norepi/Epi may be consistent with poor conversion of norepinephrine to epinephrine. This conversion is driven by the phenylethanolamine N-methyltransferase (PNMT) enzyme that requires SAMe, magnesium and cortisol (adequate HPA axis function) as cofactors.

- Consider the actual levels of both neurotransmitters, and interpret in the ratio in context of cortisol levels/HPA axis function.

- Optimization of HPA axis function may be clinically warranted.

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Ratio: Norepi/Epi

All Your Lab Results. One Simple Dashboard.

What does it mean if your Ratio: Norepi/Epi result is too high?

All Your Lab Results. One Simple Dashboard.

Import, Track, and Share Your Lab Results Easily

Import, Track, and Share Your Lab Results

Article Review & Sources

Bring All Your Lab Results Together — In One Place

Gather Your Lab History — and Finally Make Sense of It

Finally, Your Lab Results Organized and Clear

Advanced Plan

Unlimited Account

Pro Monthly

What's included in a Healthmatters membership

Import Lab Results from Any Source

See Your Health Timeline

Understand What Your Results Mean

Enter Your Lab Reports Yourself — Always Free Enter Your Lab Reports — Always Free

Visualize Your Results

Export Your Complete Lab History in a Single File Export Your Complete Lab History

Comprehensive Data Entry Service for Your Reports Data Entry Service for Your Reports

Securely Share With Anyone You Trust

Let Your Lab Results Tell the Full Story

Once your results are in one place, see the bigger picture — track trends over time, compare data side by side, export your full history, and share securely with anyone you trust.

Bring all your results together to compare, track progress, export your history, and share securely.

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All Your Lab Results.
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All Your Lab Results.
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