Phosphoserine is a product of glycolysis and is formed by amino group transfer from glutamic acid to phosphohydroxypyruvic acid. Low levels of phosphoserine may be secondary to: vitamin B6 deficiency (as coenzyme pyridoxal phosphate for amino group transfer), low pyruvic acid, impaired glycolysis, or serine insufficiency where phosphoserine is consumed as a source for serine.
Phosphoserine may be low in association with a very poor diet that is extremely low in protein, calories, B-6 and/ or magnesium. Hormonal dysfunctions, vitamin D deficiency, and calcium deficit are other possible reasons for low phosphoserine.
High levels of Phosphoserine could reflect a functional magnesium deficiency causing incomplete conversion to serine.
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1-Methylhistidine (Urine), 3-Methylhistidine (Urine), a-Amino-N-butyric Acid (Urine), a-Aminoadipic (Urine), Alanine (Urine), Anserine (dipeptide), Arginine (Urine), Asparagine (Urine), Aspartic Acid (Urine), b-Alanine (Urine), b-Aminoisobutyric Acid (Urine), Carnosine (dipeptide), Citrulline (Urine), Cystathionine (Urine), Cysteine (FMV urine), Cystine (FMV Urine), Ethanolamine (Urine), g-Aminobutyric Acid (Urine), Glutamic Acid (Urine), Glutamine (Urine), Glycine (Urine), Histidine (Urine), Isoleucine (Urine), Leucine (Urine), Lysine (Urine), Methionine (Urine), Ornithine (Urine), Phenylalanine (Urine), Phosphoethanolamine (Urine), Phosphoserine (Urine), Proline (Urine), Sarcosine (Urine), Serine (Urine), Taurine (Urine), Threonine (Urine), Tryptophan (Urine), Tyrosine (Urine), Urea (Urine), Valine (Urine)
