Phenylacetate is produced from bacterial degradation of unabsorbed phenylalanine.
In health, beneficial intestinal bacteria produce some B-vitamins and provide stimulus for proper immune function. However, if your stomach acid is not adequate, if you fail to digest protein, or if your diet does not supply sufficient fiber, the resulting overgrowth of unfavorable bacteria can release toxic products that your body must remove. These toxic products include: Phenylacetate.
Elevated Phenylacetate in the urine suggests incomplete digestion and absorption of phenylalanine in the intestine, allowing colonic bacteria to convert phenylalanine to Phenylacetate. Elevations may also reflect an overgrowth of bacteria, which convert phenylalanine to Phenylacetate.
Dietary polyphenols may also contribute to Phenylacetate elevation.
Clinical Associations: There is a clinical correlation between decreased urinary PAA and depressive symptoms.
• Malabsorption of phenylalanine
• Hypochlorhydria and/or Clostridia overgrowth
Additional investigations if high:
• Investigate possible causes of malabsorption
• IgG Food Sensitivity
Treatment considerations if high:
• Mucosal support
• Elimination diet
• Betaine HCl
• Digestive enzymes
Your potential to benefit from consuming extra sources of favorable organisms (called probiotics) may go up as the number of toxic compounds and their concentrations increase.
Own it for life
Our exclusive data entry service is a convenient way to get your results into your private dashboard. Simply attach an image or a file of your lab test results, and one of our qualified data entry team members will add the results for you. We support all sorts of files, whether PDFs, JPGs, or Excel. This service is excellent whether you have a lot of reports to upload or are too busy to do the data entry yourself.
We strive to make the data entry process easy for you. Whether by offering dozens of templates to choose from that pre-populate the most popular laboratory panels or by giving you instant feedback on the entered values. Our data entry forms are an easy, fast, and convenient way to enter the reports yourself. There is no limit on how many lab reports you can upload.
billed every month
Data entry included
$6.60/month billed annually
Data entry included
own it for life
Are You a Health Professional?
Get started with our professional plan
Welcome to Healthmatters Pro.
Save time on interpreting lab results with the largest database of biomarkers online. In-depth research on any test at your fingertips, all stored and tracked in one place. Learn more
Pro Monthly Plus
for health professionals
$75 per month