N-acetyl (2-cyanoethyl) cysteine (NACE) is a result of the exposure to acrylonitrile and NACE is the major metabolite. Acrylonitrile is a colorless liquid with a pungent odor. It is used in the production of acrylic fibers, resins, and rubber. Use of any of these products could lead to exposure to acrylonitrile. Smoking tobacco and cigarettes is another potential exposure. Exposure to acrylonitrile can lead to headaches, nausea, dizziness, fatigue, and chest pains. The European Union has classified acrylonitrile as a carcinogen.
NACE is a metabolite of acrylonitrile, which is used in the production of acrylic fibers, resins, and rubber.
Acrylonitrile is metabolized by the cytochrome P450s and then conjugated to glutathione. Elimination of acrylonitrile can be accelerated by the supplementation of glutathione (reduced) either oral, intravenous, transdermal, or its precursor N-acetyl cysteine(NAC).
Get a deeper understanding of your blood, urine, and stool test results.
$99 $79 per year
$6.60 per month billed annually
$15 per month
COVID-19 special offer!
$99 $79 per year
$250 single payment
At HealthMatters, we're committed to maintaining the security and confidentiality of your personal information. We've put industry-leading security standards in place to help protect against the loss, misuse, or alteration of the information under our control. We use procedural, physical, and electronic security methods designed to prevent unauthorized people from getting access to this information. Our internal code of conduct adds additional privacy protection. All data is backed up multiple times a day and encrypted using SSL certificates. See our Privacy Policy for more details.
2,4-Dichlorophenoxyacetic Acid (2-,4-D), 2-3-4 Methylhippuric Acid (2,-3-,4-MHA), 2-hydroxyethyl mercapturic (HEMA), 2-Hydroxyisobutyric Acid (2HIB), 3-hydroxypropylmercapturic acid (3-HPMA), 3-Phenoxybenzoic Acid (3PBA), Diethylphosphate (DEP), Dimethylphosphate (DMP), Diphenyl phosphate (DPP), Glyphosate, Monoethylphthalate (MEP), N-acetyl phenyl cysteine (NAP), N-acetyl(2-cyanoethyl)cysteine (NACE), N-acetyl(2-hydroxypropyl)cysteine (NAHP), N-acetyl(3,4-dihydroxybutyl)cysteine (NADB), N-acetyl(propyl)cysteine (NAPR), N-acetyl-S-(2-carbamoylethyl)cysteine (NAE), Perchlorate (PERC), Phenylglyoxylic Acid (PGO), Tiglylglycine