Fecal manganese (Mn) provides an indication of recent oral exposure to the element, and to a much lesser extent Mn that has been excreted from the body in bile. Manganese is an essential trace element that is naturally present in many foods and available as a dietary supplement. Oral absorption is very low (< 3%), so the vast majority of fecal Mn represents unabsorbed Mn from foods and beverages. Low oral absorption is protective because excessive retention of Mn in the body may have neurological consequences.
Manganese is present in a wide variety of foods, including whole grains, clams, oysters, mussels, nuts, soybeans and other legumes, rice, leafy vegetables, coffee, tea, and many spices, such as black pepper. Drinking water also contains Mn at variable levels, and well water Mn levels may be high. Chronic consumption of water containing high levels of Mn may lead to Mn toxicity. Caffeinated and herbal teas
tend to be high in Mn; content is higher with longer brewing/steeping time. Ninety-eight percent of absorbed Mn is normally excreted from the body via the biliary fecal route. High dietary Mn intake is not commonly associated with toxic effects of Mn unless excretion of Mn by the liver is compromised (biliary obstruction, liver failure). Manganese toxicity has occurred in people exposed to high amounts of Mn from
chronic inhalation of Mn dust/fumes (e.g. welding and mining).
Hair elemental analysis may indicate the extent of Mn exposure over the past 2-4 months.
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What does it mean if your Manganese result is too high?
Manganese is present in a wide variety of foods, including whole grains, clams, oysters, mussels, nuts, soybeans and other legumes, rice, leafy vegetables, coffee, tea, and many spices, such as black pepper. Drinking water also contains Mn at variable levels, and well water Mn levels may be high. Chronic consumption of water containing high levels of Mn may lead to Mn toxicity. Caffeinated and herbal teas
tend to be high in Mn; content is higher with longer brewing/steeping time. Ninety-eight percent of absorbed Mn is normally excreted from the body via the biliary fecal route. High dietary Mn intake is not commonly associated with toxic effects of Mn unless excretion of Mn by the liver is compromised (biliary obstruction, liver failure). Manganese toxicity has occurred in people exposed to high amounts of Mn from
chronic inhalation of Mn dust/fumes (e.g. welding and mining).
Hair elemental analysis may indicate the extent of Mn exposure over the past 2-4 months.
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