The % Lymphocyte is the proportion of white blood cells that are lymphocytes, an essential type of immune cell circulating in your bloodstream. Lymphocytes are key players in the adaptive immune system and include T cells, B cells, and natural killer (NK) cells, each critical to identifying and responding to infections, cancer cells, and other foreign threats.
Unlike a basic complete blood count (CBC), which may simply report a lymphocyte proportion, advanced immunophenotyping panels such as The Lymphocyte MAP™ provide deeper insight into immune function patterns at the cellular level, aiding clinicians in evaluating immune balance, immune deficiencies, chronic inflammation, autoimmunity, hypersensitivities, and more.
The lymphocyte percentage is typically expressed as a percentage of total white blood cells (WBCs). In healthy adults, lymphocytes usually make up about 20–40% of WBCs, though ranges can vary slightly across laboratories and populations.
Abnormal lymphocyte percentages may reflect shifts in immune activity:
High % Lymphocyte (lymphocytosis) may occur with viral infections, chronic inflammatory conditions, or certain hematologic disorders such as lymphocytic leukemia.
Low % Lymphocyte (lymphocytopenia) may be seen in acute stress responses, immunodeficiency, corticosteroid use, or advanced chronic illness.
Interpreting % Lymphocyte values in context with other immune markers (e.g., CD4, CD8, NK subsets) and clinical history provides a more complete picture of immune system status and helps guide diagnosis, monitoring, and personalized treatment strategies.
An elevated % Lymphocyte level, also called lymphocytosis, indicates that lymphocytes make up a higher-than-expected proportion of the total white blood cell (WBC) count. This pattern most often reflects immune system activation, such as during infections, inflammation, or immune dysregulation.
Lymphocytosis may be temporary and benign, especially during or after infections. However, persistently elevated levels can signal chronic immune activation, autoimmune disease, or hematologic conditions and should be evaluated in clinical context.
Viral infections (most common):
Epstein–Barr virus (EBV), cytomegalovirus (CMV), influenza, measles, rubella, hepatitis B or C, HIV, and COVID-19.
Lymphocytes expand as part of the adaptive immune response to viral replication.
Bacterial infections:
Certain infections such as pertussis (whooping cough) or tuberculosis may also cause lymphocytosis.
Parasitic infections:
Conditions such as toxoplasmosis can increase lymphocyte proportions.
Examples include:
Rheumatoid arthritis
Systemic lupus erythematosus (SLE)
Inflammatory bowel disease (IBD)
Chronic immune stimulation leads to sustained lymphocyte activation and expansion.
Conditions such as chronic lymphocytic leukemia (CLL) or certain lymphomas involve abnormal lymphocyte proliferation. These should be suspected when lymphocytosis is marked, persistent, or accompanied by abnormal cell morphology on a blood smear.
Allergic diseases (e.g., asthma, eczema, hypersensitivity reactions) may raise lymphocyte percentages as part of an overactive immune response.
Lymphocyte levels may remain elevated for weeks after an acute infection as the immune system clears residual antigens and establishes immune memory.
Severe illness, intense physical training, or psychological stress can temporarily alter white blood cell distributions, including lymphocyte percentage.
Removal of the spleen reduces lymphocyte clearance from circulation, potentially resulting in elevated lymphocyte percentages.
Symptoms depend on the underlying cause and may include:
Infection-related: fever, fatigue, sore throat, swollen lymph nodes
Autoimmune/inflammatory: joint pain, rashes, persistent inflammation
Hematologic: unexplained weight loss, night sweats, easy bruising, prolonged fatigue
Allergic: itching, respiratory symptoms, eczema
Most commonly reflects the immune system responding to infections, allergens, or antigens.
Persistent elevation may indicate unresolved infection, autoimmune disease, or chronic inflammation.
A sustained and significant increase—especially with abnormal cells—may raise concern for leukemia or lymphoma and warrants specialist evaluation.
Absolute Lymphocyte Count (ALC):
% Lymphocyte should always be interpreted alongside the absolute lymphocyte count, as a high percentage may occur even when absolute numbers are normal.
Peripheral Blood Smear:
Helps identify abnormal lymphocyte morphology suggestive of hematologic disorders.
Additional Immune Markers:
Infection-specific tests (e.g., EBV, CMV), inflammatory markers (CRP, ESR), or autoimmune markers (ANA) may help clarify the cause.
Infections: appropriate antiviral, antibacterial, or antiparasitic treatment
Autoimmune disease: immunomodulatory or anti-inflammatory therapies
Hematologic conditions: hematology referral and targeted treatment
Adequate nutrition (omega-3s, vitamin D, zinc)
Gut health support (fiber, probiotics where appropriate)
Persistent lymphocytosis should be followed over time rather than judged from a single result.
Stress-reduction strategies (sleep, moderate exercise, mindfulness) may help normalize immune signaling.
An elevated % Lymphocyte reflects how actively the immune system is responding to internal or external stimuli. While short-term increases are often normal, persistent or unexplained lymphocytosis can indicate chronic immune dysregulation, autoimmune disease, or hematologic malignancy. Identifying the underlying cause is essential for appropriate management and long-term immune health.
Import lab results from multiple providers, track changes over time, customize your reference ranges, and get clear explanations for each result. Everything is stored securely, exportable in one organized file, and shareable with your doctor—or anyone you choose.
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A low % Lymphocyte level, also known as lymphocytopenia, indicates that lymphocytes make up a lower-than-expected proportion of the total white blood cell (WBC) count. This pattern often reflects immune suppression, acute stress responses, or redistribution of immune cells, rather than an isolated immune disorder.
Low lymphocyte percentages may be temporary, especially during acute illness or stress. However, persistent or severe reductions can suggest underlying immune dysfunction or chronic disease and should be evaluated in context.
Severe physical stress, trauma, surgery, or acute infections can temporarily shift white blood cell populations, lowering the relative proportion of lymphocytes.
Medications such as corticosteroids, chemotherapy agents, or other immunosuppressive therapies can reduce circulating lymphocyte levels by suppressing production or promoting redistribution.
Some viral infections—including influenza, COVID-19, HIV, and hepatitis—may cause lymphocyte depletion during early or severe phases before immune recovery occurs.
In certain autoimmune diseases, lymphocytes may migrate from the bloodstream into tissues, resulting in lower circulating percentages despite active immune involvement.
Conditions that impair bone marrow function can reduce lymphocyte production, including:
Aplastic anemia
Myelodysplastic syndromes
Advanced malignancy
Effects of radiation or cytotoxic drugs
Deficiencies in nutrients essential for immune cell production—such as protein, zinc, folate, or vitamin B12—can contribute to lymphocytopenia.
Inherited or acquired immunodeficiency states may result in chronically low lymphocyte levels, increasing susceptibility to infections.
Symptoms depend on the underlying cause and may include:
Frequent or recurrent infections
Prolonged illness or slow recovery
Fatigue or weakness
Unexplained weight loss
Poor wound healing
Mild lymphocytopenia may cause no noticeable symptoms and be detected only through lab testing.
Temporary decreases are often seen during acute illness, stress, or medication exposure and may normalize without intervention.
Persistent reductions may indicate impaired immune surveillance or reduced lymphocyte production.
Severely low lymphocyte levels can compromise the body’s ability to mount effective immune responses.
Absolute Lymphocyte Count (ALC):
A low percentage does not always mean a low total lymphocyte count. Interpreting % Lymphocyte alongside the absolute lymphocyte count is essential.
Other White Blood Cell Subsets:
Elevated neutrophils or other leukocytes can lower the lymphocyte percentage without true lymphocyte deficiency.
Additional Immune Testing:
Subset analysis (e.g., T cells, B cells, NK cells) and functional immune testing may be recommended for persistent or unexplained lymphocytopenia.
Review medications that may suppress immune function
Treat infections or inflammatory conditions
Address bone marrow or systemic disease if present
Ensure adequate nutrition (protein, zinc, B vitamins)
Address sleep, stress, and recovery
Manage chronic inflammatory conditions appropriately
Repeat testing helps determine whether lymphocytopenia is transient or persistent.
A low % Lymphocyte can reflect temporary immune redistribution or more sustained immune suppression. While mild or short-term decreases are often benign, persistent lymphocytopenia may increase infection risk and signal underlying immune, nutritional, or bone marrow-related conditions. Proper interpretation helps guide further evaluation and immune support strategies.
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Our database covers over 10,000 biomarkers with clear, simple explanations—so you can finally understand your results and what to do next.
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Enter Your Lab Reports — Always Free
If you'd like to handle inputting your health data into your account, you can do so with our easy-to-use data entry forms. Our user-friendly form is designed to guide you through the quick and easy submission process, making it simple to keep track of your health metrics. This is available to both Complete plan and Unlimited plan members.
Our user-friendly form guides you through a quick, simple submission process, making it easy to enter your health metrics.
Add your results anytime with our easy entry form. It's quick, guided, and helps you stay organized — free for all members.
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View your lab data through easy-to-read graphs and tables. Quickly spot patterns, track changes, and compare results across different dates — all without digging through multiple reports. You can also select and compare graphs of specific biomarkers side-by-side to better understand how they relate and change over time.
See your lab reports in clear graphs and tables. Spot patterns, track changes, and compare results over time — all in one place.
Export Your Complete Lab History in a Single File
Export Your Complete Lab History
After collecting lab results from different providers, you can download your entire history combined into a single file. Choose from PDF, Excel, or CSV formats to easily review, share, or get a second opinion—no more juggling multiple reports.
After collecting lab results from different providers, you can download your entire history combined into a single file.
Comprehensive Data Entry Service for Your Reports
Data Entry Service for Your Reports
Our inclusive service handles the data entry for your lab reports. Just submit your information and we'll take care of the rest. Complete plan members receive one report entered for free, then $15 per report after that. Unlimited plan members receive ten report entries for free, then $15 per report after that.
Our inclusive service handles the data entry for your lab reports. Just submit your information and we'll take care of the rest.
Securely Share With Anyone You Trust
Whether you're working with a doctor, nutritionist, caregiver, or wellness coach, you can securely share your complete lab history by sending an invite link to anyone you trust. You have full control over who sees your information and for how long, ensuring your privacy and peace of mind at every step.
Share your full lab history with your doctor, nutritionist, or coach using a secure invite link.
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I have been using Healthmatters.io since 2021. I travel all over the world and use different doctors and health facilities. This site has allowed me to consolidate all my various test results over 14 years in one place. And every doctor that I show this to has been impressed. Because with any health professional I talk to, I can pull up historical results in seconds. It is invaluable. Even going back to the same doctor, they usually do not have the historical results from their facility in a graph format. That has been very helpful.
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As a PRO member and medical practitioner, Healthmatters.io has been an invaluable tool for tracking my clients' data. The layout is intuitive, making it easy to monitor trends and spot patterns over time. The ability to customize reports and charts helps me present information clearly to my clients, improving communication and outcomes. It's streamlined my workflow, saving me time and providing insights at a glance. Highly recommended for any practitioner looking for a comprehensive and user-friendly solution to track patient labs!
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Healthmatters is a personal health dashboard that helps you organize and understand your lab results. It collects and displays your medical test data from any lab in one secure, easy-to-use platform.
With a Healthmatters account, you can:
Professionals can also analyze client data more efficiently and save time managing lab reports.
Healthmatters.io personal account provides in-depth research on 4000+ biomarkers, including information and suggestions for test panels such as, but not limited to:
You can combine all test reports inside your Healthmatters account and keep them in one place. It gives you an excellent overview of all your health data. Once you retest, you can add new results and compare them.
If you are still determining whether Healthmatters support your lab results, the rule is that if you can test it, you can upload it to Healthmatters.
While we work with many popular labs, we welcome reports from lots of other places too.
It's as simple as this: if you can get a test done, you can upload it to Healthmatters and we can interpret results from any lab out there. If laboratories can analyze it, we can interpret it.
If you're on the hunt for a specific biomarker, contact us and we'll add it to our database. Anything from blood, urine, saliva, or stool can be uploaded, understood, and tracked with your Healthmatters account.
The Complete Plan ($15/month) is perfect for individuals who want ongoing access to their health data. It includes unlimited lab imports, visual tracking, custom ranges, result explanations, full account exports, and secure sharing — all with a simple monthly subscription. You can cancel anytime and restart your plan whenever you're ready — your data will still be there waiting for you. You can also upgrade to the Unlimited Plan at any time, with the cost prorated based on what you've already paid.
The Unlimited Plan ($250 one-time) is also designed for individuals but offers lifetime access with no ongoing subscription. You'll get all the same features as the Complete Plan, plus a larger initial data entry allowance (10 reports), making it a great choice if you prefer a one-time payment and long-term use without monthly fees.
In short:
There are two ways to add your test reports to your Healthmatters account. One option is to input the data using the data entry forms. The other method is to utilize our "Data entry service."
Our data entry forms offer an easy, fast, and free way for you to input the reports yourself. Self-entry allows you to add an unlimited number of reports at no cost. We make the self-entry process user-friendly, providing dozens of templates that pre-populate the most popular laboratory panels and offering instant feedback on entered values.
For those who prefer assistance, we offer a "Data entry service" to help you input your data. Simply attach an image or file of your lab test results, and a qualified team member from our data entry team will add the results for you.
We support various file types, including PDFs, JPGs, or Excel. This service is particularly useful if you have many reports to upload or if you're too busy to handle the data entry yourself.
Our Data Entry Service is for when you don't want to manually type in your lab results yourself. You simply upload your report (PDF, image, or screenshot), and our trained team enters the information into your Healthmatters account for you — accurately and neatly organized, ready to view in graphs, tables, and timelines.
The $15 per report covers the time and care it takes for a real person to review your file, make sure each result is entered correctly, and double-check for accuracy. This ensures your health data is precise and easy to work with — without you having to spend the time doing it yourself.
Prefer to do it yourself? You can always use our free self-entry tool to add results manually — it just takes a bit more time and attention.
For users on the Complete monthly plan, the first report is entered free of charge, and each additional report incurs a fee of $15.
Unlimited account holders enjoy the entry of ten reports without charge. Subsequent reports are subject to a $15 fee per report.
Additionally, users on the Complete plan can upgrade to a yearly subscription from the account settings. The annual subscription includes a data entry service for five reports.
All professional accounts allow you to import and onboard an unlimited number of clients and their lab results. The distinction between professional plans lies solely in the data entry service.
The Pro Monthly Plus plan is priced at $75 per month and includes a data entry service for five reports each month. Additional reports can be self-entered at no extra cost or, if preferred, you can use our data entry service for an additional fee of $15 per report.
The Pro Monthly plan is priced at $45 per month and does not include a data entry service. Self-entry is free for an unlimited number of reports, and you can opt for the data entry service at a fee of $15 per report.
You also have the option to upgrade to higher monthly or to annual plans, which come with substantial discounts. All upgrades can be done directly from your account.
Simply log in and navigate to your account settings to cancel your subscription. Scroll down to locate the 'Cancel' button at the bottom of the page. Ensure you cancel at least one day before the renewal date to prevent any charges. Once cancellation is requested, the subscription remains active until the conclusion of the current billing cycle.
Our goal has been to make your Healthmatters account as intuitive as possible.
We've crafted multiple ways for you to navigate your data, whether you're glancing at a single report or delving into your historical test reports.
1. Graph View:Dive into a visual journey with our biomarker graphs, showcasing over 40 data points. Combining years of results unveils trends, empowering you to make informed decisions. Our visualization tools make it a breeze to compare and understand changes over time, even if your results are from different labs. A search function and filters simplify the exploration of extensive data, allowing you to focus on what needs attention.
2. All Tests ViewExplore neatly organized reports on a timeline, highlighting crucial details like dates, critical results, and lab/panel names. Each report opens up to reveal in-depth descriptions and additional recommendations for each biomarker. The history of previous results is just a click away, and you can download a comprehensive report for deeper insights. Color-coded and user-friendly, it's designed for easy reading, understanding, and navigation.
3. Table View:For a holistic view of all biomarkers side by side, our table view is your go-to. Results are neatly displayed in a categorized and dated table, ideal for those with an extensive test history. Utilize sorting, filters, and color-coding to enhance your analysis and gain extra insights.
Yes, you can download your information anytime. We offer two easy ways to export your lab data:
This makes it simple to save, back up, or share your health data whenever you need.
Yes, you can print your report. To do so, navigate to "All tests" and open the report you wish to print. You'll find a print button in the right corner of the report. Click on it, and your browser's print window will open. If you prefer to print in a bigger typeface, adjust the scale using the print window settings.
Yes, you can! We highly recommend activating Two-Factor Authentication (2FA) for your account. To do so, please navigate to the "Profile and Security" section of your account, where you will find instructions for activating 2FA.
Yes, you can. When entering values for the biomarker, you will see an "Edit Range" button. Click this button, and you'll have the option to enter a custom range.
A personal account is all about keeping your own lab test results in check. It's just for you and your personal use.
The professional account is designed for health professionals who wish to track and organize their clients' laboratory results.
To learn more about Healthmatters Pro, please refer to the professional page.
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Optimal Result:
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