Human Herpesvirus-6 (HHV-6), belonging to the beta-herpesvirus subfamily, is a lymphotropic virus, which infects mainly T cells in vitro, causes acute and latent infections. Most humans acquire HHV-6 during early childhood and after initial infection, the virus latently remains in the host. HHV-6 is capable of persisting in the host after primary infection for many years. Salivary glands and brain tissue are suspected of harboring persistent HHV-6 infection. Candidate sites for latency are monocytes and early bone marrow progenitor cells.
Increased risk of chronic fatigue syndrome, fibromyalgia, lupus, and autoimmunities of the nervous system, joints and thyroid.
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