Optimal Result: 200 - 1000 µg/mL.

The pancreatic elastase 1 fecal test is used to diagnose insufficiencies of the pancreas that result in diseases such as:

- Cystic fibrosis

- Chronic pancreatitis

- Pancreatic cancer

- Inflammatory Bowel Disease

- Gallstones

- Diabetes, Type 1

- Shwachman-Diamond Syndrome

In many of these conditions, there is often diarrhea, weight loss, undigested food in the stool, and pain in the abdomen. If the condition continues for a longer period of time, then low bone density may be found.

This test is an excellent biomarker for how well the pancreas is working because the enzyme pancreatic elastase I is not broken down by what happens in the intestinal tract. The Elastase I protein is found concentrated in the stool, five times higher than what is found in pancreatic juice. 

What does it mean if your Elastase result is too low?

The lower the level of Pancreatic Elastase I is in the stool, the worse the pancreatic insufficiency is. 

Doctors find that the following conditions are associated with low levels of pancreatic elastase I:

- Cystic fibrosis

- Chronic pancreatitis

- Pancreatic cancer

- Inflammatory Bowel Disease

- Gallstones

- Diabetes, Type 1

- Shwachman-Diamond Syndrome

What does it mean if your Elastase result is too high?

There are no problems recorded in medical literature for high levels of Pancreatic Elastase I. 

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