Essential and Metabolic Fatty Acids Markers (RBCs)

Docosatetraenoic

Optimal Result: 1.5 - 4.2 wt %.

Docosatetraenoic Acid is one of these Omega-6 Polyunsaturated Fatty Acids:

– Linoleic Acid

– Gamma Linolenic Acid

– Eicosadienoic Acid

– Dihomogamma Linolenic Acid

– Arachidonic Acid

– Docasadienoic

– Docosatetraenoic Acid

Docosatetraenoic acid is also known as Adrenic acid / Adrenate.

Docosatetraenoic acid is a member of the class of compounds known as very long-chain fatty acids.

Fatty acids belong to one of three types or families: saturatedmonounsaturated and polyunsaturated. These names describe the structure of the fatty acid in terms of whether it is fully loaded with hydrogen.

References:

– Health Implications of High Dietary Omega-6 Polyunsaturated Fatty Acids [L]

– Significance of long chain polyunsaturated fatty acids in human health [L]

– Adrenic acid as an inflammation enhancer in non-alcoholic fatty liver disease. [L]

– Plasma fatty acid profile as biomarker of coronary artery disease: a pilot study using fourth generation artificial neural networks. [L]

– Association of Plasma Phospholipid n-3 and n-6 Polyunsaturated Fatty Acids with Type 2 Diabetes: The EPIC-InterAct Case-Cohort Study [L]

What does it mean if your Docosatetraenoic result is too high?

When omega-6 dietary fatty acids are consumed in abundance, there is an accumulation of desaturation and elongation intermediates. Diets high in fat and simple sugars contribute to obesity and to the accumulation of docosatetraenoic acid.

Increases in polyunsaturated fatty acids can lead to chronic inflammatory diseases such as:

– nonalcoholic fatty liver disease (NAFLD),

– cardiovascular disease,

– type 2 diabetes,

– obesity, inflammatory bowel disease (IBD),

– rheumatoid arthritis,

– and Alzheimer’s disease (AD).

Potential Responses: Weight control / Glycemic control

Metabolic Association: Increase in adipose tissue

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