A healthy result should fall into the range 20 - 750 ng/mg.
DHEA is produced in the adrenal glands and is a precursor to both testosterone and estrogen. DHEA also affects bone density, response to stress, mood and cognitive function, improves insulin sensitivity, and is associated with decreased cardiovascular and cancer risk. It peaks in the mid-20s and begins to decline after 30. Longevity is associated with higher than age-normal levels of DHEA. Low levels may be a sign of adrenal stress and/or reduced androgen production.
Causes of decreased DHEA:
- Declines with age (> 35 y.o.)
- Prednisone ingestion
- Adrenal insufficiency
Causes of increased DHEA:
- DHEA supplementation
- Tribulus or Rhodiola supplementation
- Congenital adrenal hyperplasia
- Adult onset adrenal hyperplasia
- Adrenal neoplasm
- High dose pregnenolone supplementation
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