DHEA-S is the sulfate ester of DHEA and only a part of DHEA testing.
Age-Dependent Ranges for DHEA-S:
Age: DHEA-S:
20-39 60-750
40-60 30-350
>60 20-150
Understanding DHEA:
- DHEA (Dehydroepiandrosterone) is an endogenous steroid hormone made by both men and women in the adrenal gland, predominantly, and to a lesser degree in the brain and gonads.
- DHEA helps produce other hormones, including testosterone and estrogen. Natural DHEA levels peak in early adulthood and then slowly fall as you age.
- You will see that the three big DHEA urine markers are: DHEA-S, Etiocholanolone (metabolite) and Androsterone (metabolite).
- It is important to note that DHEA and not DHEA-S makes testosterone and/or estrone (E1)
Possible scenarios:
DHEA-S low / Androsterone low / Etiocholanolone low:
--> Overall DHEA production is low. Look at the main DHEA marker for more details.
DHEA-S low / Androsterone normal / Etiocholanolone normal:
- Because inflammation blocks DHEA being converted to DHEA-S, consider inflammation as a potential part of the overall picture when DHEA-S is significantly lower than the downstream metabolites of DHEA (Androsterone, Etiocholanolone). Look at actue and chronic inflammation disorders (e.g. Rheumatoid arthritis).
Understand and improve your laboratory results with our health dashboard.
Upload your lab reports and get your interpretation today.
Our technology helps to understand, combine, track, organize, and act on your medical lab test results.
DHEA-S levels can be high because overall DHEA levels are high.
- Stress: DHEA will also increase in response to cortisol. DHEA can counter the effect of cortisol in the brain. So if you have a lot of stress in your life the high DHEA level might be lowered by reducing overall stress and potentially supplements to get the cortisol back into the normal range. Once the cortisol issue has been addressed the DHEA might come down as well if it was related.
- In addition, medications such as Ritalin, Xanax (alprazolam), Wellbutrin (bupropion), Arimidex, Norvasc (amlodipine), Procardia, diltiazem, and alcohol will raise DHEA levels.
- High DHEA levels can be associated with PCOS.
- DHEA supplementation. If your androgenic metabolism favors the 5-alpha pathway, you might get androgenic side effects (irritation, facial hair, losing scalp hair, angriness, etc). Look at the downstream metabolites to see if you favor the alpha pathway.
Interpret Your Lab Results
Upload your lab report, and we'll interpret and provide you with recommendations today.
Get StartedOur specialized data entry service is designed to seamlessly integrate your laboratory results into your private dashboard. Just send in your lab test results—whether it's an image or a file—and our skilled data entry team will handle the rest. We accommodate various file formats like PDFs, JPGs, and Excel.
The first report is complimentary. After that, the data entry service is priced at $15 per report, unless it's part of your subscribed plan. It's an ideal solution whether you have numerous reports to upload or if your schedule doesn't permit self-data entry.
We strive to make the data entry process easy for you. Whether by offering dozens of templates to choose from that pre-populate the most popular laboratory panels or by giving you instant feedback on the entered values. Our data entry forms are an easy, fast, and convenient way to enter the reports yourself. There is no limit on how many lab reports you can upload.
Personal plans
track personal results
Professional Plan
track multiple client's results
$15/month
$250/once
own it for life
$45/month
for health professionals
Personal Account
$15/month
for personal lab results
$250/once
own it for life
Level up your lab report analysis with our Pro plan, built for health practitioners like you.
Health Business Account
$45/month
Unlock additional Pro plans when you sign up.
At HealthMatters, we're committed to maintaining the security and confidentiality of your personal information. We've put industry-leading security standards in place to help protect against the loss, misuse, or alteration of the information under our control. We use procedural, physical, and electronic security methods designed to prevent unauthorized people from getting access to this information. Our internal code of conduct adds additional privacy protection. All data is backed up multiple times a day and encrypted using SSL certificates. See our Privacy Policy for more details.
5a-Androstanediol, 5a-Androstanediol (male), 5a-DHT, 5a-DHT (male), 5b-Androstanediol, 5b-Androstanediol (male), Androsterone, Androsterone (male), DHEA-S (Urine), DHEA-S (Urine) (male), Epi-Testosterone, Epi-Testosterone (male), Etiocholanolone, Etiocholanolone (male), Testosterone (DUTCH), Testosterone (DUTCH) (male), Total DHEA Production