DHEA-S (Urine) (male)

A healthy result should fall into the range 30 - 1500 ng/mg.

DHEA is produced in the adrenal glands and is a precursor to both testosterone and estrogen. DHEA also affects bone density, response to stress, mood and cognitive function, improves insulin sensitivity, and is associated with decreased cardiovascular and cancer risk. It peaks in the mid-20s and begins to decline after 30. Longevity is associated with higher than age-normal levels of DHEA. Low levels may be a sign of adrenal stress and/or reduced androgen production.

Age-Dependent Ranges:

20-39: 150-1500

40-60: 60-800

>60: 30-300

DHEA-S (Urine) (male) result calculator

insert the value from you DHEA-S (Urine) (male) test result.

What does it mean if your DHEA-S (Urine) (male) result is too low?

A decrease in DHEA sulfate may be due to:

  • Adrenal gland disorders that produce lower than normal amounts of adrenal hormones, including adrenal insufficiency and Addison disease
  • The pituitary gland not producing normal amounts of its hormones (hypopituitarism)
  • Taking glucocorticoid medicines

DHEA levels normally decline with age in both men and women. There is no reliable evidence that taking DHEA supplements prevents aging-related conditions.

What does it mean if your DHEA-S (Urine) (male) result is too high?

An increase in DHEA-sulfate may be due to:

  • DHEA supplementation (androsterone and etiocholanolone may also increase)
  • Congenital adrenal hyperplasia (pregnanetriol may also be elevated)
  • Adult-onset adrenal hyperplasia (pregnanetriol may also be elevated) (May present as anxiety)
  • Adrenal neoplasm
  • High-dose pregnenolone supplementation
  • A tumor of the adrenal gland, which can be benign or be a cancer.

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