Choline is used for:
- Epigeneticgeneregulation
- Precursortolipoproteins
- Phospholipids
- Acetylcholine
Choline is an essential dietary nutrient found in many foods. Here are some of the sources:
- vegetables, including broccoli, potatoes, and mushrooms
- whole grains, such as quinoa, rice, and whole wheat bread
- nuts and seeds
- proteins, such as beef, soybeans, fish, poultry, and eggs
Choline can be made endogenously, but dietary intake is needed to prevent deficiency. Choline is a critical cell membrane component. It also helps to ensure the structural integrity and signaling functions within the cell. Choline is a precursor for the important neurotransmitter acetylcholine and the membrane phospholipids phosphatidylcholine and sphingomyelin.
In the methylation cycle, choline is oxidized to form betaine, which can then be used as a methyl donor. Because choline and betaine are involved in the re-methylation of homocysteine back to methionine, they form a backup-pathway that is particularly favored in folate deficiency.
---------------------
References:
https://pubmed.ncbi.nlm.nih.gov/18716669/
https://pubmed.ncbi.nlm.nih.gov/20446114/
- Low intake
- Malabsorption / maldigestion
Understand and improve your laboratory results with our health dashboard.
Upload your lab reports and get your interpretation today.
Our technology helps to understand, combine, track, organize, and act on your medical lab test results.
- Too much dietary intake (i.e. meat, eggs, soybeans, and wheat germ, etc)
- Upregulation of the betaine/choline backup pathway
Elevated choline levels are associated with key components of metabolic syndrome (dysglycemia, dyslipidemia, and BMI). Betaine showed an opposite relationship. This may suggest a disruption of mitochondrial choline oxidation to betaine as part of the mitochondrial dysfunction seen in metabolic syndrome.
Choline is a major lipotrophe, responsible for creating VLDL. Elevated plasma choline is positively associated with:
- Triglycerides
- Glucose
- BMI
- Body fat
- Waist circumference
Interpret Your Lab Results
Upload your lab report, and we'll interpret and provide you with recommendations today.
Get StartedOur specialized data entry service is designed to seamlessly integrate your laboratory results into your private dashboard. Just send in your lab test results—whether it's an image or a file—and our skilled data entry team will handle the rest. We accommodate various file formats like PDFs, JPGs, and Excel.
The first report is complimentary. After that, the data entry service is priced at $15 per report, unless it's part of your subscribed plan. It's an ideal solution whether you have numerous reports to upload or if your schedule doesn't permit self-data entry.
We strive to make the data entry process easy for you. Whether by offering dozens of templates to choose from that pre-populate the most popular laboratory panels or by giving you instant feedback on the entered values. Our data entry forms are an easy, fast, and convenient way to enter the reports yourself. There is no limit on how many lab reports you can upload.
Personal plans
track personal results
Professional Plan
track multiple client's results
$15/month
$250/once
own it for life
$45/month
for health professionals
Personal Account
$15/month
for personal lab results
$250/once
own it for life
Level up your lab report analysis with our Pro plan, built for health practitioners like you.
Health Business Account
$45/month
Unlock additional Pro plans when you sign up.
At HealthMatters, we're committed to maintaining the security and confidentiality of your personal information. We've put industry-leading security standards in place to help protect against the loss, misuse, or alteration of the information under our control. We use procedural, physical, and electronic security methods designed to prevent unauthorized people from getting access to this information. Our internal code of conduct adds additional privacy protection. All data is backed up multiple times a day and encrypted using SSL certificates. See our Privacy Policy for more details.
Betaine, Betaine/Choline Ratio, Choline, Cyst(e)ine, Cystathionine, Dimethylglycine (DMG), Glutathione, Glycine, Homocysteine, Met/Sulf Balance Ratio, Methionine, Methylation Balance Ratio, Methylation Index (SAM/SAH Ratio), S-adenosylhomocysteine (SAH), S-adenosylmethionine (SAM), Sarcosine, Serine, Taurine