Cholic Acid on Labcorp's Bile Acids, Fractionated LC/MS-MS Panel
Labcorp's Bile Acids, Fractionated and Total, LC/MS-MS is a comprehensive assay that quantifies various bile acids, including cholic acid, in their free, glycine-conjugate, and taurine-conjugate forms. This test utilizes high-pressure liquid chromatography coupled with tandem mass spectrometry (LC/MS-MS) to provide detailed insights into bile acid profiles.
Cholic Acid Overview
Cholic acid is a primary bile acid synthesized in the liver from cholesterol. It plays a crucial role in the emulsification and absorption of dietary fats and fat-soluble vitamins in the small intestine. Cholic acid is also involved in regulating cholesterol levels and maintaining the integrity of the intestinal mucosa.
Clinical Significance
Measurement of cholic acid levels is valuable in assessing:
-
Cholestatic Liver Diseases: Elevated bile acid levels, including cholic acid, can indicate impaired bile flow, as seen in conditions like intrahepatic cholestasis of pregnancy (ICP).
-
Bile Acid Synthesis Disorders: Abnormal cholic acid levels may suggest defects in bile acid synthesis pathways.
-
Gallbladder Function: Cholic acid levels can reflect gallbladder motility and bile secretion efficiency.
Cholic Acids
Every lab result you’ve ever had, charted and explained.
Healthmatters is a tracker for your lab results. Upload a report from any lab, any country — every marker charted and explained.
Start with my report →
All our content is backed by peer-reviewed studies, academic research, and trusted medical sources. We’re committed to accuracy and transparency — see our editorial policy for details.