% CD57+ CD8+ T Cell

Whole Blood
Optimal Result: 9.2 - 16.6 %.

The marker % CD57+ CD8+ T cells provides insightful data into an individual's immune status, specifically reflecting the subset of natural killer T cells (NKT-like cells) that exhibit both CD57 and CD8 markers.

CD57, a marker for terminal differentiation, is expressed on a subset of T cells that have undergone extensive proliferation and are associated with senescence and a high degree of cytotoxic potential.

CD8+ T cells, on the other hand, are crucial components of the adaptive immune system, responsible for directly killing infected or cancerous cells.

The co-expression of CD57 on CD8+ T cells marks a highly differentiated cell population with potent cytotoxic function but reduced proliferative capacity.

This subset is often increased in chronic viral infections and certain autoimmune diseases, indicating an ongoing immune response. The Lymphocyte MAP panel, by quantifying the percentage of CD57+ CD8+ T cells, provides valuable insights into the immune system's current state of activation and its potential exhaustion levels. This information can be pivotal for clinicians in diagnosing, monitoring, and potentially tailoring treatment strategies for various conditions, including chronic infections, autoimmune diseases, and cancer. It underscores the importance of detailed immune profiling in understanding disease mechanisms and the immune system's capacity to respond to pathogens and malignancies.

What does it mean if your % CD57+ CD8+ T Cell result is too low?

The marker % CD57+ CD8+ T Cell is a significant indicator of the immune system's health, specifically reflecting the status of natural killer T cells (NKT) and their interaction with the overall immune response. CD57 is a surface marker found on a subset of natural killer (NK) cells and T lymphocytes, and when it is co-expressed with CD8 (a co-receptor that is primarily expressed on the surface of cytotoxic T cells), it identifies a unique population of cells that are involved in the body's defense against viral infections and possibly in the control of certain types of cancer.

Decreased levels of % CD57+ CD8+ T cells can signify an impaired immune response, which may be due to various factors, including chronic viral infections, such as Human Immunodeficiency Virus (HIV) or Hepatitis C Virus (HCV), autoimmune diseases, or long-term exposure to immune-suppressing treatments. In some cases, low counts of these cells have been associated with chronic fatigue syndrome (CFS) and other immune dysregulation syndromes, indicating their importance in immune surveillance and homeostasis. The assessment of these cells can, therefore, provide critical insights into the status of an individual's immune health, guiding potential therapeutic interventions.

Frequently asked questions

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For our professional users, Healthmatters provides intuitive tools that not only streamline analysis but also save valuable time when delving into your client's lab report history.

Healthmatters.io personal account provides in-depth research on 4000+ biomarkers, including information and suggestions for test panels such as, but not limited to:

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While we work with many popular labs, we welcome reports from lots of other places too.

It's as simple as this: if you can get a test done, you can upload it to Healthmatters and we can interpret results from any lab out there. If laboratories can analyze it, we can interpret it.

If you’re on the hunt for a specific biomarker, contact us and we'll add it to our database. Anything from blood, urine, saliva, or stool can be uploaded, understood, and tracked with your Healthmatters account.

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Our data entry forms offer an easy, fast, and free way for you to input the reports yourself. Self-entry allows you to add an unlimited number of reports at no cost. We make the self-entry process user-friendly, providing dozens of templates that pre-populate the most popular laboratory panels and offering instant feedback on entered values.

For those who prefer assistance, we offer a "Data entry service" to help you input your data. Simply attach an image or file of your lab test results, and a qualified team member from our data entry team will add the results for you.

We support various file types, including PDFs, JPGs, or Excel. This service is particularly useful if you have many reports to upload or if you're too busy to handle the data entry yourself.

Our special data entry service makes it easy to add your results to your private dashboard. Just attach an image or a file of your lab test results, and our skilled data entry team will do the work for you. It's all done by humans, ensuring that your data is entered accurately and with personal care for each client.

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For users on the Complete monthly plan, the first report is entered free of charge, and each additional report incurs a fee of $15.

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Additionally, you can upgrade to the yearly Advanced plan from within your account. The annual cost is $79, and it comes with a data entry service for five reports.

You can always upgrade to a lifetime version with a prorated price from a monthly or yearly subscription.

Simply log in and navigate to your account settings to cancel your subscription. Scroll down to locate the 'Cancel' button at the bottom of the page. Ensure you cancel at least one day before the renewal date to prevent any charges. Once cancellation is requested, the subscription remains active until the conclusion of the current billing cycle.

Our goal has been to make your Healthmatters account as intuitive as possible.

We’ve crafted multiple ways for you to navigate your data, whether you're glancing at a single report or delving into your historical test reports.

1. Graph View:

Dive into a visual journey with our biomarker graphs, showcasing over 40 data points. Combining years of results unveils trends, empowering you to make informed decisions. Our visualization tools make it a breeze to compare and understand changes over time, even if your results are from different labs. A search function and filters simplify the exploration of extensive data, allowing you to focus on what needs attention.

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Explore neatly organized reports on a timeline, highlighting crucial details like dates, critical results, and lab/panel names. Each report opens up to reveal in-depth descriptions and additional recommendations for each biomarker. The history of previous results is just a click away, and you can download a comprehensive report for deeper insights. Color-coded and user-friendly, it's designed for easy reading, understanding, and navigation.

3. Table View:

For a holistic view of all biomarkers side by side, our table view is your go-to. Results are neatly displayed in a categorized and dated table, ideal for those with an extensive test history. Utilize sorting, filters, and color-coding to enhance your analysis and gain extra insights.

Yes, you can download information from your account. We can compile your labs into a CSV file. To download all your labs, you can go to Account Settings, and at the bottom of the page, you will find a link to download your information.

Yes, you can print your report. To do so, navigate to "All tests" and open the report you wish to print. You'll find a print button in the right corner of the report. Click on it, and your browser's print window will open. If you prefer to print in a bigger typeface, adjust the scale using the print window settings.

Yes, you can! We highly recommend activating Two-Factor Authentication (2FA) for your account. To do so, please navigate to the "Profile and Security" section of your account, where you will find instructions for activating 2FA.

Yes, you can. When entering values for the biomarker, you will see an "Edit Range" button. Click this button, and you'll have the option to enter a custom range.

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