Infectious Disease Profile

Beta-2 Microglobulin, Serum

Optimal Result: 0.6 - 2.4 mg/L.

Beta-2 microglobulin is a protein that is found on the surface of the majority of cells in the human body and is shed by the cells into the blood.

Beta2-microglobulin is abundant on the surface of white blood cells. Increased production or destruction of these cells causes Beta2-microglobulin levels in the blood to increase. This increase is seen in people with cancers involving white blood cells, but it is particularly meaningful in people newly diagnosed with multiple myeloma. Multiple myeloma is a cancer of a certain kind of white blood cell, called a plasma cell. At the time of diagnosis, the Beta2-microglobulin levels reflect how advanced the disease is and the likely prognosis for that person.

Because Beta-2 Microglobulin is increased with blood cell cancers, it may be useful as a tumor marker. Though it can be used to assess kidney function as well.

References:

What does it mean if your Beta-2 Microglobulin, Serum result is too low?

  • Low levels of Beta2-microglobulin (as a tumor marker) are considered normal and good.
  • When kidney disease is suspected, comparing blood and urine levels helps identify where the kidney is damaged.

What does it mean if your Beta-2 Microglobulin, Serum result is too high?

  • Elevated concentration levels of beta-2 microglobulin is attributed to diseases with a high cell turnover. It is a powerful prognosis factor for multiple myeloma, a type of bone marrow cancer. It is also used to detect chronic lymphocytic leukemia and some types of lymphomas.
  • In glomerular kidney disease, the glomeruli can’t filter it out of the blood, so levels increase in the blood and decrease in the urine.
  • After a kidney transplant, increased blood levels may be an early sign of rejection, toxic amounts of anti-rejection medication, or a viral infection.
  • An increased level in a worker exposed to cadmium or mercury may signal beginning kidney damage.
  • Possible virus infection (ex: cytomegalovirus or HIV).

Understand blood, stool, and urine medical results from your labs.

10 000+ happy clients
100% satisfaction
★★★★★ customer support

Essential Plan


  • Monthly subscription
  • Instant interpretation
  • Use the free self-upload form
  • Additional charge for upload service
  • 2000+ biomarkers explained
  • Recommendations
  • Cancel anytime

Advanced Plan


  • Yearly subscription
  • Instant interpretation
  • We upload five reports for you
  • Use the free self-upload form
  • 2000+ biomarkers explained
  • Nutrition Recommendations
  • Online support
  • Cancel anytime

Own It For Life premium plan


  • No subscription
  • Unlimited access
  • Unlimited storage
  • Instant interpretations
  • We upload ten reports for you
  • Use the free self-upload form
  • 2000+ biomarkers explained
  • Nutrition Recommendations
  • Dedicated support

Healthmatters.io software for professional use.

Welcome to Healthmatters Pro.

Save time on interpreting lab results with the largest database of biomarkers online. In-depth research on any test at your fingertips, all stored and tracked in one place.

Learn More


We implement proven measures to keep your data safe.

At HealthMatters, we're committed to maintaining the security and confidentiality of your personal information. We've put industry-leading security standards in place to help protect against the loss, misuse, or alteration of the information under our control. We use procedural, physical, and electronic security methods designed to prevent unauthorized people from getting access to this information. Our internal code of conduct adds additional privacy protection. All data is backed up multiple times a day and encrypted using SSL certificates. See our Privacy Policy for more details.

General Data Protection Regulation (GDPR). HIPAA compliance for healthcare professionals
×

Understand Your Lab Result Now

  • Instant interpretation
  • 2000+ biomarkers explained
  • Science-based recommendations
  • Online support
  • Secure and private portal

Get 10% off with promocode:

;