b-Pregnanediol (postmenopausal range)

Optimal Result: 60 - 200 ng/mg.

Pregnanediol is a metabolite of the molecule of progesterone, which is important for fertility and for menstruation. Pregnanediol levels increase after ovulation and when the placenta releases the hormone. 

When pregnanediol levels fall during a menstrual cycle, it means that progesterone levels are less than ideal. It results in symptoms during the luteal phase. 

During the adaptation of the body to menopause, progesterone levels fall and estrogen dominance begins. That’s when progesterone supplements may be offered to manage the symptoms. Some of the symptoms include hot flashes, vaginal dryness, mood instability, low sex drive, sleep problems, brain fog, hair loss, loss of muscle mass and strength, weight gain and anxiety.

Various normal ranges*:

  • Luteal (premenopausal) Range: 2000 - 9000 ng/mg
  • Postmenopausal Range: 60-200 ng/mg
  • Follicular Range: 100-300 ng/mg
  • Ovulatory Range: 100-300 ng/mg
  • Oral Progesterone (100mg) - Range: 2000-9000 ng/mg

*the Luteal Range is the premenopausal range. When patients are taking oral progesterone this range for progesterone metabolites is not luteal and reflects the higher levels expected when patients take oral progesterone. This test is intended to be taken in the luteal phase of the menstrual cycle (days 19-22 of a 28 day cycle) for premenopausal women.

Sources:

  1. http://www.labtesthelp.com/test/Pregnanediol
  2. http://meridianvalleylab.com/wp-content/uploads/2016/06/Urine-Hormone-Interp-Guide.pdf
  3. https://www.gdx.net/product/complete-hormones-test-urine 

What does it mean if your b-Pregnanediol (postmenopausal range) result is too low?

You can have low levels of pregnanediol as well as high levels. 

Low levels of pregnanediol are associated with any of the following:  

- Breast or ovarian cancer

- Pre-eclampsia (high blood pressure during pregnancy)

- When a mother is carrying a baby that is dead

- When the placenta fails

- When menstruation stops

- Sleep disturbances

- Anxiety and stress

- Edema or swelling in the body

What does it mean if your b-Pregnanediol (postmenopausal range) result is too high?

High progesterone metabolites can occur with progesterone or pregnenolone supplementation. 

It can also occur with stress as the adrenals release more progesterone during stress, although ovarian production will exceed adrenal production with ovulation.

High progesterone is also seen in PCOS when ovulation occurs because of excessive luteinizing hormone secretion. Some women may naturally make high levels of progesterone and, if symptom free, it is usually not concerning. Symptoms of high progesterone may include bloating, fatigue and food cravings, especially high calorie foods.

10 000+ happy customers
100% satisfaction
★ ★ ★ ★ ★ customer support

Understand blood, stool, and urine medical results from all your laboratories.

Upload Your Personal Results

Upload Personal Results

For professional account plans go here

for professional account plans go here

Monthly plan

Annual plan

Own it for life

  • Subscription
  • Data entry service included

    Data entry service

    Our exclusive data entry service is a convenient way to get your results into your private dashboard. Simply attach an image or a file of your lab test results, and one of our qualified data entry team members will add the results for you. We support all sorts of files, whether PDFs, JPGs, or Excel. This service is excellent whether you have a lot of reports to upload or are too busy to do the data entry yourself.

  • Instant interpretation
  • Use free data entry form

    Free data entry form

    We strive to make the data entry process easy for you. Whether by offering dozens of templates to choose from that pre-populate the most popular laboratory panels or by giving you instant feedback on the entered values. Our data entry forms are an easy, fast, and convenient way to enter the reports yourself. There is no limit on how many lab reports you can upload.

  • 4000+ biomarkers explained
  • Nutrition recommendations
  • Cancel anytime

Complete

$15 /month

billed every month

  • monthly
  • $15 per report
  • ✓ Instant interpretations
  • ✓ 4000+ biomarkers explained
  • ✓ Nutrition recommendations
  • ✓ Free data entry form
  • ✓ Unlimited data
  • ✓ $15 data entry service
  • ✓ Cancel anytime

Most popular

Data entry included

Advanced

$79 /year

$6.60/month billed annually

  • yearly
  • 5 reports free
  • ✓ Instant interpretations
  • ✓ 4000+ biomarkers explained
  • ✓ Nutrition recommendations
  • ✓ We enter 5 reports for you
  • ✓ Yearly subscription
  • ✓ Cancel anytime

Data entry included

Unlimited

$250 /once

own it for life

  • pay once
  • 10 reports free
  • ✓ Instant interpretations
  • ✓ 4000+ biomarkers explained
  • ✓ Nutrition recommendations
  • ✓ We enter 10 reports for you
  • ✓ No subscription
  • ✓ Dedicated support
  • ✓ Unlimited access

Are You a Health Professional?

Get started with our professional plan

Welcome to Healthmatters Pro.

Save time on interpreting lab results with the largest database of biomarkers online. In-depth research on any test at your fingertips, all stored and tracked in one place. Learn more

Pro Monthly Plus

for health professionals

  • ✓ Track multiple clients results
  • ✓ No setup fees
  • ✓ No hidden costs
  • ✓ Instant interpretations
  • ✓ 4000+ biomarkers explained
  • ✓ Includes data entry service
  • ✓ Personal training and support
  • ✓ Cancel anytime

$75 per month

Use promo code to save 10% off any plan.


We implement proven measures to keep your data safe.

At HealthMatters, we're committed to maintaining the security and confidentiality of your personal information. We've put industry-leading security standards in place to help protect against the loss, misuse, or alteration of the information under our control. We use procedural, physical, and electronic security methods designed to prevent unauthorized people from getting access to this information. Our internal code of conduct adds additional privacy protection. All data is backed up multiple times a day and encrypted using SSL certificates. See our Privacy Policy for more details.