Anti-Acetylcholine receptors (IgG + IgA)

Optimal Result: 0.1 - 10 Units.

Acetylcholine receptors are responsible for binding acetylcholine, a neurotransmitter for signal transduction in CNS. They are localized in neuromuscular junctions. Antibodies against acetylcholine receptor are found in myasthenia gravis disease, which destroys the receptor function, leading to a neuromuscular transmission defect, which then causes hypofunction, fatigue, and inflammation of skeletal muscles and produces serum antibodies against muscle antigens.

References:

Lee JJ, Koh KM, Kim US. The anti-acetylcholine receptor antibody test in suspected ocular myasthenia gravis. J Ophthalmol. 2014;2014:689792. doi: 10.1155/2014/689792. Epub 2014 Nov 13. PMID: 25478208; PMCID: PMC4247930.

What does it mean if your Anti-Acetylcholine receptors (IgG + IgA) result is too high?

Acetylcholine receptors are responsible for binding acetylcholine, a neurotransmitter for signal transduction in CNS. They are localized in neuromuscular junctions. Antibodies against acetylcholine receptor are found in myasthenia gravis disease, which destroys the receptor function, leading to a neuromuscular transmission defect, which then causes hypofunction, fatigue, and inflammation of skeletal muscles and produces serum antibodies against muscle antigens.

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