Androgens and Metabolites (Urine) - DUTCH

Androsterone (male)

Optimal Result: 500 - 3000 ng/mg.

Androsterone and Etiocholanolone are DHEA metabolites via Androstenedione and the 5α- and 5β-reductase pathways. These androgens allow assessment of 5α-reductase activity. Normal metabolites may be a better indicator of androgen status in a patient with low DHEA and/or testosterone.

What does it mean if your Androsterone (male) result is too low?

Causes of low Androsterone levels: 

- Declines as DHEA declines

- adrenal insufficiency

- anorexia nervosa

- panhypopituitarism

What does it mean if your Androsterone (male) result is too high?

High levels are often seen in PCOS and with over-supplementation.

Other causes of high Androsterone levels:

- DHEA, pregnenalone supplementation

- Androgen producing gonadal tumors

- Congenital adrenal hyperplasia

- Adult onset adrenal hyperplasia

- Serious illness/ shock - burns, etc.

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