Antigen Made From:
Amaranth flour
Associated With:
- Allergy
Known Cross-Reactions:
Quinoa, Rice, Sunflower; Insulin, Glutamic Acid Decarboxylase-65; Triiodothyronine (T3)
Clinical Significance:
The presence of antibodies to Amaranth is an indication of food immune reactivity. The offending food and its known cross-reactive foods should be eliminated from the diet. Amaranth is considered a beneficial food, especially for patients with cardiovascular disease and hypertension, due to its ability to reduce blood pressure and cholesterol.
Amaranth is also an excellent anti-oxidant. Amaranth labeled by the scientific community as a non-allergenic food, however, allergy to Amaranth has been reported. If a recently diagnosed gluten-reactive patient exhibits high levels of antibodies to Amaranth, it may be
due to the late introduction of Amaranth into the diet.
References:
1. Mozzicato and Bedard. Anaphylaxis to an Organic Health Food Cereal: Amaranth Allergy. (2009, October). Poster presented
at: 2009 New England Society of Allergy Fall Meeting: Boston, MA and 2009 Connecticut ACP Annual Scientific and Associates
Meeting: Southington, CT.
2. Aphalo et al. Surface physicochemical properties of globulin-P amaranth protein. J Agric Food Chem, 2004; 52:616-622.
3. Czerwinski et al. Oat (Avena sativa L.) and amaranth (Amaranthus hypochondriacus) meals positively affect plasma lipid profile in
rats fed cholesterol-containing diets. J Nutr Biochem, 2004; 15:622-629.
4. Martirosyan et al. Amaranth oil application for coronary heart disease and hypertension. Lipids Health Dis, 2007; 6(1):1-12.
5. Kharrazian, et al. Detection of islet cell immune reactivity with low glycemic index foods: is this a concern for type 1 diabetes? J
Diabetes Res, 2017; 2017:4124967.
6. Kharrazian, et al. Immunological reactivity using monoclonal and polyclonal antibodies of autoimmune thyroid target sites with
dietary proteins. J Thyroid Res, 2017; 2017:4354723.
Amaranth
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