Allopregnanolone is the main metabolite of progesterone.
Allopregnanolone is a potent positive allosteric modulator of the GABAA receptor. Allopregnanolone has a wide variety of effects, including antidepressant, anxiolytic, stress-reducing, pro-sleep, sedative, neuroprotective, cognitive, and analgesic.
Fluctuations in the levels of allopregnanolone and the other neurosteroids seem to play an important role in the pathophysiology of mood, anxiety, premenstrual syndrome, catamenial epilepsy, and various other neuropsychiatric conditions.
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Fluctuations in the levels of allopregnanolone and the other neurosteroids seem to play an important role in the pathophysiology of mood, anxiety, premenstrual syndrome, catamenial epilepsy, and various other neuropsychiatric conditions.
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11-Deoxycortisol, 17OH-Progesterone, 7-keto DHEA, Aldosterone, Allopregnanolone (Oral or Topical Progesterone), Anastrozole, Androstenedione, Corticosterone, Cortisol (morning), Cortisone (Morning), DHEA, DHEAS, DHEAS (Age Dependent), DHT, Estradiol [Premenopausal (Luteal)], Estriol (Premenopausal Luteal), Estrone (Premeno-luteal), Ethinyl Estradiol, Finasteride, Letrozole, Melatonin, Pregnenolone Sulfate, Progesterone [Premenopausal (Luteal)], Progesterone [Top, Troche, Vag Pg (10-30mg)], Ratio: DHEA/7keto DHEA, Ratio: Pg/E2, Ratio: Pg/E2 (Saliva LCMS), Testosterone, Testosterone (Age Dependent)