ZRT Laboratory (Salivary Steroids)

Allopregnanolone (Oral or Topical Progesterone)

Optimal Result: 0 - 111.5 pg/mL.

Allopregnanolone is the main metabolite of progesterone.

Allopregnanolone is a potent positive allosteric modulator of the GABAA receptor. Allopregnanolone has a wide variety of effects, including antidepressant, anxiolytic, stress-reducing, pro-sleep, sedative, neuroprotective, cognitive, and analgesic.

What does it mean if your Allopregnanolone (Oral or Topical Progesterone) result is too low?

Fluctuations in the levels of allopregnanolone and the other neurosteroids seem to play an important role in the pathophysiology of mood, anxiety, premenstrual syndrome, catamenial epilepsy, and various other neuropsychiatric conditions.

What does it mean if your Allopregnanolone (Oral or Topical Progesterone) result is too high?

Fluctuations in the levels of allopregnanolone and the other neurosteroids seem to play an important role in the pathophysiology of mood, anxiety, premenstrual syndrome, catamenial epilepsy, and various other neuropsychiatric conditions.

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