Optimal Result:
0 - 20 Units.
Alistipes is a genus of Gram-negative, anaerobic bacteria that resides primarily in the large intestine as part of the normal human gut microbiome. It is considered a commensal organism, but its clinical significance depends heavily on overall microbiome balance, inflammatory status, and host immune function.
Research has linked Alistipes to a wide range of health states. In balanced amounts, it may participate in normal microbial metabolism and bile acid processing. However, elevated levels have been associated with gut dysbiosis, chronic low-grade inflammation, depressive symptoms, and certain metabolic or inflammatory conditions. Conversely, reduced levels have been observed in some inflammatory bowel diseases and states of reduced microbial diversity.
Alistipes is particularly notable for its involvement in the gut–brain axis. Alterations in its abundance have been correlated with mood disorders, stress-related conditions, and systemic inflammation, suggesting that it may influence immune signaling and neuroinflammatory pathways.
On advanced panels such as the Gut Zoomer Alistipes is not interpreted in isolation. Its significance depends on coexisting findings such as inflammatory markers, short-chain fatty acid production, microbial diversity, and gut barrier integrity. This context-driven interpretation helps distinguish whether Alistipes is acting as a neutral commensal, a marker of dysbiosis, or a contributor to inflammatory burden.
Lab Results Explained and Tracked
What does it mean if your Alistipes result is too high?
Elevated Alistipes levels are commonly associated with gut dysbiosis and increased inflammatory signaling. High values may correlate with digestive discomfort, systemic inflammation, metabolic imbalance, or mood-related symptoms, particularly when accompanied by elevated inflammatory or immune markers.
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