A healthy result should fall into the range 0 - 0.3 ng/mg.
Research and clinical studies show that the 2-hydroxylated estrogens (2-OH E2 and 2-OH E1) are a safer pathway of hydroxylation than the 4-hydroxyestrogens (4-OH E2 and 4-OH E1), which bind to and damage DNA, leading to mutations that are associated with increased breast cancer risk. If either 4-OH-E2 or 4-OH-E1 are higher than reference range, and not well methylated, this may indicate higher risk for DNA damage, mutations, and risk for developing breast cancer.
Hydroxylation of estrogens in the 2-position of estradiol (2-OH-E2) and estrone (2-OH-E1) is considered a safer pathway for metabolism than the 4-position hydroxylations of these estrogens. The 2-position hydroxylations (considered safer) are increased with cruciferous vegetables (and extracts of them) as well as iodine. The most commonly used are indole-3-carbinol (I3C) and its metabolite diindolylmethane (DIM). Iodine also increases the 2-hydroxylation of estrogens, with a slight increase in 4-hydroxylation. The more dangerous 4-hydroxylated estrogen metabolism is enhanced by exposure to environmental toxins, mostly petrochemical-based products but also heavy metals, that induce 4-hydroxylation pathway enzymes, and cause formation of Reactive Oxygen Species (ROS) that co-oxidize the catechol estrogens to more dangerous estrogen quinones.
insert the value from you 2-OH-E2 Postmenopausal test result.
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16-OH-E1, 16-OH-E1 (male), 16-OH-E1 Postmenopausal, 2-Methoxy-E1, 2-Methoxy-E1 (male), 2-Methoxy-E1 Postmenopausal, 2-Methoxy-E2, 2-Methoxy-E2 Postmenopausal, 2-OH-E1, 2-OH-E1 (male), 2-OH-E1 Postmenopausal, 2-OH-E2, 2-OH-E2 Postmenopausal, 24hr Free Cortisol, 24hr Free Cortisone, 4-OH-E1, 4-OH-E1 (male), 4-OH-E1 Postmenopausal, 4-OH-E2, 4-OH-E2 Postmenopausal, 5-Hydroxyindoleacetate (5HIAA), 5a-Androstanediol, 5a-Androstanediol (male), 5a-DHT, 5a-DHT (male), 5b-Androstanediol, 5b-Androstanediol (male), 8-OHdG (Waking), a-Pregnanediol (luteal range), a-Pregnanediol (male), a-Pregnanediol (oral progesterone range), a-Pregnanediol (postmenopausal range), a-Tetrahydrocortisol (a-THF), a-Tetrahydrocortisol (a-THF) (male), Androsterone, Androsterone (male), b-Pregnanediol (luteal range), b-Pregnanediol (male), b-Pregnanediol (oral progesterone range), b-Pregnanediol (postmenopausal range), b-Tetrahydrocortisol (b-THF), b-Tetrahydrocortisol (b-THF) (male), b-Tetrahydrocortisone (b-THE), b-Tetrahydrocortisone (b-THE) (male), Cortisol A (Waking), Cortisol B (Morning), Cortisol C (Afternoon), Cortisol D (Night), Cortisone A (Waking), Cortisone B (Morning), Cortisone C (Afternoon), Cortisone D (Night), Creatinine A (Waking), Creatinine B (Morning), Creatinine C (Afternoon), Creatinine D (Night), DHEA-S (Urine), DHEA-S (Urine) (male), Epi-Testosterone, Epi-Testosterone (male), Estradiol (E2), Estradiol (E2) (male), Estradiol (E2) Postmenopausal, Estriol (E3), Estriol (E3) (male), Estriol (E3) Postmenopausal, Estrone (E1), Estrone (E1) Postmenopausal, Estrone(E1) (male), Etiocholanolone, Etiocholanolone (male), Homovanillate (HVA) (DUTCH), Kynurenate, Melatonin (Waking), Metabolized Cortisol (THF+THE), Metabolized Cortisol (THF+THE) (male), Methylmalonate (MMA) (DUTCH), Progesterone, Pyroglutamate, Saliva Cortisol - Afternoon, Saliva Cortisol - Night, Saliva Cortisol - W+30 min., Saliva Cortisol - W+60 min., Saliva Cortisol - Waking, Saliva Cortisol Total, Saliva Cortisone - Afternoon, Saliva Cortisone - Night, Saliva Cortisone - W+30 min, Saliva Cortisone - W+60 min., Saliva Cortisone - Waking, Saliva Cortisone Total, Testosterone (DUTCH), Testosterone (DUTCH) (male), Total DHEA Production, Total Estrogen, Total Estrogen (male), Total Estrogen Postmenopausal, Vanilmandelate (VMA), Xanthurenate
