While the traditional 2/16 ratio clinical utility may not be as robust as previously thought, a majority of findings indicate that metabolism of parent estrogens through 2-hydroxylation (independent of any relationship to 16α-OHE1) may be considered as a benign or even protective pathway.
Note: Moderation should be used, however, in up-regulating the "lesser estrogenic" 2- hydroxylation pathway, particularly in women with a positive family history of osteoporosis, since excessive 2-hydroxylation has been associated with decreased bone mineral density
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11-Hydroxy-androsterone (FMV urine, menopause), 11-Hydroxy-etiocholanolone (FMV urine, menopause), 11-Keto-androsterone (FMV urine, menopause), 11-Keto-etiocholanolone (FMV urine, menopause), 16a-Hydroxyestrone (16a-OH E1) / Menopause, 17 - Hydroxysteroids Total (FMV urine, menopause), 17 - Ketosteroids Total (FMV urine, menopause), 17-Hydroxysteroids, Total (menopause), 17-Ketosteroids, Total (FMV urine, menopause), 2-Hydroxyestrone + 2-Hydroxyestradiol [2-OH(E1+E2)] / Menopause, 2-Methoxyestrone+2-Methoxyestradiol [2MeO(E1+E2)] / Menopause, 2-OH(E1+E2) / 16a-OHE1 (Menopause), 2-OH(E1+E2) / 2-MeO(E1+E2) / Menopause, 4-Hydroxyestrone+4-Hydroxyestradiol [4-OH(E1+E2)] / Menopause, 4-Methoxyestrone+4-Methoxyestradiol [4MeO(E1+E2)] / Menopause, allo-Tetrahydrocortisol, a-THF (FMV urine, menopause), Anabolic/Catabolic Balance (FMV), Anabolic/Catabolic Balance (FMV, menopause), Androstanediol (FMV urine, menopause), Androsterone (FMV urine, menopause), DHEA (FMV urine, menopause), E/A: 5b/5a Ratio (FMV urine, menopause), Estradiol (FMV urine, menopause), Estriol (FMV urine, menopause), Estrone (FMV urine, menopause), Etiocholanolone (FMV urine, menopause), Pregnanediol (FMV urine, menopause), Pregnanetriol (FMV urine, menopause), Testosterone (FMV urine, menopause), Tetrahydrocortisol, THF (FMV urine, menopause), Tetrahydrocortisone, THE (FMV urine, menopause), Tetrahydrodeoxycortisol (FMV urine, menopause)
