11-deoxycortisol is an adrenal hormone. It is the end product of 17-hydroxyprogesterone (17OHPg) through 21-hydroxylase synthesis and is the immediate precursor of cortisol.
Levels of these cortisol precursors and the enzymes that stimulate cortisol synthesis from them are typically increased when ACTH levels are increased, which can occur with Cushing syndrome, adrenal carcinoma, ACTH-producing tumors, or 11β-hydroxylase deficiency, a more rare form of CAH34 than seen with 21-hydroxylase deficiency, which constitutes > 95% of all CAH cases
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Levels of these cortisol precursors and the enzymes that stimulate cortisol synthesis from them are typically increased when ACTH levels are increased, which can occur with Cushing syndrome, adrenal carcinoma, ACTH-producing tumors, or 11β-hydroxylase deficiency, a more rare form of CAH34 than seen with 21-hydroxylase deficiency, which constitutes > 95% of all CAH cases
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11-Deoxycortisol, 17OH-Progesterone, 7-keto DHEA, Aldosterone, Allopregnanolone (Oral or Topical Progesterone), Anastrozole, Androstenedione, Corticosterone, Cortisol (morning), Cortisone (Morning), DHEA, DHEAS, DHEAS (Age Dependent), DHT, Estradiol [Premenopausal (Luteal)], Estriol (Premenopausal Luteal), Estrone (Premeno-luteal), Ethinyl Estradiol, Finasteride, Letrozole, Melatonin, Pregnenolone Sulfate, Progesterone [Premenopausal (Luteal)], Progesterone [Top, Troche, Vag Pg (10-30mg)], Ratio: DHEA/7keto DHEA, Ratio: Pg/E2, Ratio: Pg/E2 (Saliva LCMS), Testosterone, Testosterone (Age Dependent)
