Hyperparathyroidism is a condition where the parathyroid glands in the neck produce too much parathyroid hormone (PTH), which regulates calcium levels in the body. It's mainly classified into two types: primary and secondary.
Primary hyperparathyroidism, more common, occurs when one or more of the parathyroid glands become overactive, often due to a benign tumor, leading to high calcium levels in the blood. This can cause symptoms like fatigue, bone pain, kidney stones, and mood changes.
Secondary hyperparathyroidism, typically caused by chronic kidney disease or vitamin D deficiency, happens when the body's low calcium levels trigger the parathyroid glands to produce more PTH.
In both types, diagnosis involves blood tests to check calcium and PTH levels, and sometimes imaging tests to examine the glands. Treatment depends on the cause and severity, ranging from regular monitoring to surgery for removing overactive glands in primary hyperparathyroidism or addressing the underlying cause in secondary hyperparathyroidism. It's important to manage this condition, as untreated hyperparathyroidism can lead to complications like weakened bones, kidney problems, and cardiovascular issues.
Biomarkers related to this condition:
Parathyroid hormone (PTH) helps the body maintain stable levels of calcium in the blood. It is part of a feedback loop that includes calcium, PTH, vitamin D, and, to some extent, phosphorus (phosphate) and magnesium. Conditions and diseases that disr