Severe, painful neurological and gastrointestinal symptoms occur from thallium poisoning; alopecia is the most characteristic sign, as it is coupled with a black pigment at the hair root. Nausea, vomiting, and diarrhea have been reported. Thallium exposure may occur due to soil contamination with thallium-containing pesticides although they have been banned since 1972. Specimens used for thallium detection include urine, which is the main route of excretion, and hair. Blood levels have been measured, but thallium is rapidly cleared, so exposure must be acute to achieve accurate results. Treatment for high thallium levels include Prussian blue, DMSA, or activated charcoal for ingested thallium. BAL, D-penicillamine and EDTA are contraindicated.
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