Non-Crenated Erythrocytes (CSF) refer to red blood cells (RBCs) in cerebrospinal fluid (CSF) that maintain their normal, smooth, biconcave shape. Their presence typically indicates a more recent or acute introduction of blood into the CSF, such as from a traumatic injury, subarachnoid hemorrhage, or traumatic lumbar puncture. Unlike crenated erythrocytes, which form after prolonged exposure to CSF or osmotic stress, non-crenated erythrocytes suggest fresh bleeding or damage. Elevated levels of non-crenated erythrocytes often accompany other markers of acute trauma or hemorrhage and require further evaluation with imaging studies and additional CSF analysis to identify the source and extent of the underlying issue.
Non-Crenated Erythrocytes (CSF)
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