Hair is a reasonable tissue for monitoring accumulated body stores of Nickel (Ni). However, hair is OFTEN contaminated with Ni from hair treatments, dyes, and hair products. There is substantial evidence that Ni is an essential element which is required in extremely low amounts. However, excess Ni has been well established to be nephrotoxic, and carcinogenic. Elevated Ni is often found in individuals who work in the electronic and plating, mining, and steel manufacture industries. A cigarette typically contains from 2 to 6 mcg of Ni; Ni is absorbed more efficiently in the lungs (~35%) than in the gastrointestinal tract (~5%).
Symptoms of chronic Ni exposure include dermatitis, chronic rhinitis, and hypersensitivity reactions. Ni can hypersensitize the immune system, subsequently causing hyperallergenic responses to many different substances. Symptoms of Ni toxicity are dermatitis and pulmonary inflammation (following exposure to Ni dust, smoke). Long term or chronic Ni toxicity may lead to liver necrosis and carcinoma. A confirmatory test for elevated Ni is the measurement of urine Ni before and after administration of complexing agents that mobilize Ni (e.g., DMPS, EDTA).
Sources Of Nickel
- cigarette smoking
- commercial peanut butter
- herring
- hydrogenated vegetable oils
- imitation whip creams
- kelp
- imitation whip creams
- margarine
- nickel plating
- oysters
- tea
- unrefined grains and cereals
- vegetable shortening
- vegetarian products
manufacture of: steel, batteries, machine parts, wire, electrical parts
How Nickel Affects The Body
| Kidneys - | nickel has a tendency to accumulate in the kidneys. | |
| Hormone, Lipid and Membrane Metabolism - |
It is believed that nickel has some physiological role related to these functions. |
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Hair Analysis Notes
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Normal nickel is about 0.1 mg% or lower.
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More research is needed regarding the physiological roles and significance of hair levels of nickel.
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