N-acetyl (propyl)cysteine (NAPR) is a metabolite of 1-bromopropane, which is an organic solvent used for metal cleaning, foam gluing, and dry cleaning. Studies have shown that 1-BP is a neurotoxin as well as a reproductive toxin. Research indicates that exposure to 1-BP can cause sensory and motor deficits. Chronic exposure can lead to decreased cognitive function and impairment of the central nervous system. Acute exposure can lead to headaches. Individuals who have high levels of 1-bromopropane should examine their environment to determine their exposure route. 1- bromopropane elimination can be accelerated by the supplementation of glutathione (reduced) either oral, intravenous, transdermal, or its precursor N-acetyl cysteine(NAC).
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