Lignoceric C24:0

Intake of foods containing these VLSFAs or use of products containing them can contribute to higher levels. Increased intake of precursor fatty acids, or SNPs in the elongase enzyme, may alter levels.

The health implications of elevated VLSFAs levels are evolving, though they are generally found to be beneficial in health and aging. Several meta-analyses suggest a beneficial association of very long chained saturated fatty acids with cardiovascular health outcomes as well as lower risks of type 2 diabetes, atrial fibrillation, heart failure, and coronary disease. These VLSFAs may also be important in neural development and cognition. The mechanisms of these very long chained saturated fatty acids are not fully known. Because VLSFAs are components of ceremides involved in apoptosis, there is strong evidence that VLSFAs are protective against apoptosis and cell death.

Lignoceric acid has 24 carbons and no double bonds (24:0). It can be formed from behenic acid using the elongase enzyme. It is found in peanuts, nut and seed oils. It can also be found in wood tar. Lignoceric acid is one of many fatty acids which compose brain tissue and myelin.

Decreased dietary intake of saturated fatty acids, or avoidance of products containing them, can result in low levels. Some VLSFAs can be synthesized from other fatty acids. Therefore, decreased levels of precursors, lack of vitamin and mineral cofactors, or SNPs in the elongase enzyme may also contribute to low levels.

Specific deficiency in VLSFAs is not well studied. Though, due to their importance in brain development and their associations with improved health outcomes, as outlined above, research is evolving.

Lignoceric acid has 24 carbons and no double bonds (24:0). It can be formed from behenic acid using the elongase enzyme. It is found in peanuts, nut and seed oils. It can also be found in wood tar. Lignoceric acid is one of many fatty acids which compose brain tissue and myelin.