Eubacterium is a genus of gram-positive bacteria. They are one of the most abundant species in healthy colons and use lactate and acetate to produce butyrate, and 1,2 propanediol to produce propionate. Depletion of Eubacterium rectale has been associated with high fat diets, colorectal cancer and ulcerative colitis. Species belonging to this genus are also involved in the metabolism of polyphenols - health-promoting metabolites, which can reduce incidence of carcinogenesis. Eubacterium rely on sources of resistant starches for survival.
References:
Engels, C., Ruscheweyh, H.-J., Beerenwinkel, N., Lacroix, C. & Schwab, C. The Common Gut Microbe Eubacterium hallii also Contributes to Intestinal Propionate Formation. Front. Microbiol. 7, 713 (2016).
Flint, H. J., Scott, K. P., Louis, P. & Duncan, S. H. The role of the gut microbiota in nutrition and health. Nat. Rev. Gastroenterol. Hepatol. 9, 577–589 (2012).
Wang, T. et al. Structural segregation of gut microbiota between colorectal cancer patients and healthy volunteers.
Vermeiren, J. et al. Decreased colonization of fecal Clostridium coccoides/Eubacterium rectale species from ulcerative colitis patients in an in vitro dynamic gut model with mucin environment. FEMS Microbiol. Ecol. 79, 685– 696 (2012).
Cardona, F., Andrés-Lacueva, C., Tulipani, S., Tinahones, F. J. & Queipo-Ortuño, M. I. Benefits of polyphenols on gut microbiota and implications in human health. J. Nutr. Biochem. 24, 1415–1422 (2013).
Eubacterium rectale
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