2-Hydroxyestrone
Optimal Result:
2 - 8.4 ng/mg CR.
2-Hydroxyestrone is a metabolite of estrogen and is often referred to as a "good" estrogen due to its relatively benign nature compared to other estrogen metabolites. The significance of 2-Hydroxyestrone lies in its role in the 2-hydroxylation pathway, one of the primary routes through which the body metabolizes estrogens. This metabolite is considered to have weaker estrogenic activity and is associated with a reduced risk of estrogen-related cancers, such as breast cancer, in contrast to other pathways that produce more potent and potentially harmful estrogen metabolites. The ratio of 2-Hydroxyestrone to other estrogen metabolites, particularly 16-alpha-hydroxyestrone, is often analyzed as it provides valuable information about the overall estrogenic activity and potential cancer risk in the body. Elevated levels of 2-Hydroxyestrone, or a favorable ratio of 2-Hydroxyestrone to other metabolites, is generally seen as protective. In the FU Female FMV Urine Comprehensive Hormone panel, measuring 2-Hydroxyestrone helps in assessing a woman's estrogen metabolism status, which is crucial for understanding hormone-related health conditions, guiding hormone replacement therapy, and managing the risk of estrogen-sensitive diseases. This marker's inclusion in the panel underscores the importance of comprehensive hormonal profiling in women's health, particularly in personalized medicine approaches.
Lab Results Explained and Tracked
What does it mean if your 2-Hydroxyestrone result is too high?
Elevated levels of 2-Hydroxyestrone in a FU Female FMV Urine Comprehensive Hormone panel generally indicate an increased activity in the 2-hydroxylation pathway of estrogen metabolism. This is often considered a positive sign, as 2-Hydroxyestrone is known as a 'good' estrogen metabolite due to its weaker estrogenic activity compared to other metabolites, and it is associated with a lower risk of estrogen-related health issues, such as certain types of breast cancer. However, it's important to interpret these levels in the context of the overall hormonal balance and health status of the individual.
If the 2-Hydroxyestrone levels are disproportionately high compared to other estrogen metabolites, it might suggest an imbalance in estrogen metabolism. Treatment in such cases often focuses on lifestyle and dietary changes. For instance, increasing the intake of cruciferous vegetables (like broccoli, cauliflower, and Brussels sprouts) that promote 2-hydroxylation, and maintaining a healthy body weight can help balance estrogen metabolism. Regular exercise is also beneficial.
In some cases, supplements like diindolylmethane (DIM) or indole-3-carbinol (I3C) might be recommended, as they are known to support the 2-hydroxylation pathway. However, it's crucial to approach any treatment plan under the guidance of a healthcare professional who can assess the overall hormonal profile and recommend a personalized treatment plan. The goal is to maintain a healthy balance of estrogen metabolites, which is essential for overall hormonal health and well-being.
All Your Lab Results.
One Simple Dashboard.
Import, Track, and Share Your Lab Results Easily
Import, Track, and Share Your Lab Results
Import lab results from multiple providers, track changes over time, customize your reference ranges, and get clear explanations for each result. Everything is stored securely, exportable in one organized file, and shareable with your doctor—or anyone you choose.
Cancel or upgrade anytime
Article Review & Sources
All our content is backed by peer-reviewed studies, academic research, and trusted medical sources. We're committed to accuracy and transparency — see our editorial policy for details.
Laboratories
Bring All Your Lab Results Together — In One Place
We accept reports from any lab, so you can easily collect and organize all your health information in one secure spot.
Pricing Table
Gather Your Lab History — and Finally Make Sense of It
Finally, Your Lab Results Organized and Clear
Personal plans
$79/ year
Advanced Plan
Access your lab reports, explanations, and tracking tools.
- Import lab results from any provider
- Track all results with visual tools
- Customize your reference ranges
- Export your full lab history anytime
- Share results securely with anyone
- Receive 5 reports entered for you
- Cancel or upgrade anytime
$250/ once
Unlimited Account
Pay once, access everything—no monthly fees, no limits.
- Import lab results from any provider
- Track all results with visual tools
- Customize your reference ranges
- Export your full lab history anytime
- Share results securely with anyone
- Receive 10 reports entered for you
- No subscriptions. No extra fees.
$45/ month
Pro Monthly
Designed for professionals managing their clients' lab reports
- Import lab results from any provider
- Track lab results for multiple clients
- Customize reference ranges per client
- Export lab histories and reports
- Begin with first report entered by us
- Cancel or upgrade anytime
About membership
What's included in a Healthmatters membership
Import Lab Results from Any Source
See Your Health Timeline
Understand What Your Results Mean
Visualize Your Results
Data Entry Service for Your Reports
Securely Share With Anyone You Trust
Let Your Lab Results Tell the Full Story
Once your results are in one place, see the bigger picture — track trends over time, compare data side by side, export your full history, and share securely with anyone you trust.
Bring all your results together to compare, track progress, export your history, and share securely.
What Healthmatters Members Are Saying
I have been using Healthmatters.io since 2021. I travel all over the world and use different doctors and health facilities. This site has allowed me to consolidate all my various test results over 14 years in one place. And every doctor that I show this to has been impressed. Because with any health professional I talk to, I can pull up historical results in seconds. It is invaluable. Even going back to the same doctor, they usually do not have the historical results from their facility in a graph format. That has been very helpful.
Anthony
Unlimited Plan Member since 2021
What fantastic service and great, easy-to-follow layouts! I love your website; it makes it so helpful to see patterns in my health data. It's truly a pleasure to use. I only wish the NHS was as organized and quick as Healthmatters.io. You've set a new standard for health tracking!
Karin
Advanced Plan Member since 2020
As a PRO member and medical practitioner, Healthmatters.io has been an invaluable tool for tracking my clients' data. The layout is intuitive, making it easy to monitor trends and spot patterns over time. The ability to customize reports and charts helps me present information clearly to my clients, improving communication and outcomes. It's streamlined my workflow, saving me time and providing insights at a glance. Highly recommended for any practitioner looking for a comprehensive and user-friendly solution to track patient labs!
Paul
Healthmatters Pro Member since 2024
We implement proven measures to keep your data safe.
At HealthMatters, we're committed to maintaining the security and confidentiality of your personal information. We've put industry-leading security standards in place to help protect against the loss, misuse, or alteration of the information under our control. We use procedural, physical, and electronic security methods designed to prevent unauthorized people from getting access to this information. Our internal code of conduct adds additional privacy protection. All data is backed up multiple times a day and encrypted using SSL certificates. See our Privacy Policy for more details.
