Pneumo Ab Type 68 (9V)

Serum
Optimal Result: 1.3 - 10 ug/ml.

This test measures IgG antibody levels to Streptococcus Pneumoniae to determine how well a person has responded to vaccination.

What is Streptococcus Pneumoniae (pneumococcal)?

Streptococcus Pneumoniae (pneumococcal) is a bacteria that is responsible for the majority of cases of pneumonia as well as other conditions including bronchitis, septicemia, and meningitis. Pneumonia is most dangerous for young children, people over the age of 65, or those with other conditions that are already weakening their immune system.

What are the types of pneumococcal vaccines?

Several types of pneumococcal vaccines are available. The 2 most common vaccines are Prevnar13 (PCV13) and Pneumovax23 (PPSV23).

PCV13 provides protection from 13 pneumococcus serotypes and PPSV23 provides protection from 23 serotypes.

Depending on a person's age and other risk factors, they may be recommended to take one or both vaccines. After being vaccinated, a blood test can help to verify that a person has developed sufficient levels of IgG antibodies to protect them from infection.

When is this antibody test ordered?

Antibody testing is typically ordered after someone has completed taking the pneumococcus vaccine to verify that they have developed sufficient antibody levels for protection.

What is considered a normal response?

A response to 50-70 percent or more of the serotypes in the vaccine challenge is considered a normal humoral response.

Antibody concentration greater than 1.3 µg/mL is generally considered long-term protection.

References:

Song CH, Estevez D, Chernikova D, Hernandez F, Sakai-Bizmark R, Stiehm R. Low Baseline Pneumococcal Antibody Titers Predict Specific Antibody Deficiency, Increased Upper Respiratory Infections, and Allergy Sensitization. Allergy Rhinol (Providence). 2020 Jan 22;11:2152656719900338. doi: 10.1177/2152656719900338. PMID: 32030313; PMCID: PMC6977093.

Sorensen RU, Edgar D. Specific Antibody Deficiencies in Clinical Practice. J Allergy Clin Immunol Pract. 2019 Mar;7(3):801-808. doi: 10.1016/j.jaip.2019.01.024. Epub 2019 Jan 23. PMID: 30682575.

What does it mean if your Pneumo Ab Type 68 (9V) result is too low?

Normally people should generate a response to more than half of the pneumococcal serotypes in the vaccine. 

Low baseline pneumococcal antibody titers predict specific antibody deficiency, increased upper respiratory infections, and allergy sensitization

People with low pneumococcal antibody levels should receive a booster vaccination with pneumococcal polysaccharide vaccine (pneumovax 23) with responses evaluated 4-6 weeks following immunization.

Note: Pneumococcal polysaccharide vaccine should not be given to patients younger than age 2 years - polysaccharide antigen responses in this age group are unreliable. 

Frequently asked questions

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Simply log in and navigate to your account settings to cancel your subscription. Scroll down to locate the 'Cancel' button at the bottom of the page. Ensure you cancel at least one day before the renewal date to prevent any charges. Once cancellation is requested, the subscription remains active until the conclusion of the current billing cycle.

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We’ve crafted multiple ways for you to navigate your data, whether you're glancing at a single report or delving into your historical test reports.

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For a holistic view of all biomarkers side by side, our table view is your go-to. Results are neatly displayed in a categorized and dated table, ideal for those with an extensive test history. Utilize sorting, filters, and color-coding to enhance your analysis and gain extra insights.

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Yes, you can. When entering values for the biomarker, you will see an "Edit Range" button. Click this button, and you'll have the option to enter a custom range.

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