The cancer antigen 27.29 test (CA 27.29) is a blood test that measures the levels of glycoprotein produced by the mucin-1 (MUC1) gene.
The level of CA 27.29, also known as 27.29, is used as a tumor marker to measure the activity of the disease in patients with breast cancer. It’s one of several types of tumor markers used for breast cancer and is most commonly used in advanced breast cancer, as opposed to early-stage breast cancer.
What is a CA 27.29 test used for?
What is the difference between CA 15-3 and CA 27.29?
Another type of tumor marker, CA 15-3, also measures a similar antigen, but doctors generally choose one test or the other. They aren’t often used interchangeably for the same patient.
CA 27.29 levels and normal range
After a CA 27.29 test, doctors interpret the test results, which are measured in units per milliliter (U/mL). The normal range of CA 27.29 is 0 to 38 U/mL. If a patient’s CA 27.29 is elevated, this may indicate that further tests are needed.
However, every patient’s situation is unique, so it’s important for patients to speak to their doctor about specific CA 27.29 results and what they mean.
While CA 27.29 levels may be elevated due to metastatic breast cancer, they may also be raised by other health conditions, including:
- Other cancer types
- Localized breast cancer
- Some noncancerous conditions
Ongoing cancer treatment may also impact CA 27.29 levels, since chemotherapy may increase levels in the body immediately after treatment. For this reason, doctors may wait to administer a CA 27.29 test until after the patient has finished a round of active treatment.
While it’s normal for patients to feel anxious or worried when waiting for results, CA 27.29 fluctuations over time may occur, so test results are only one part of the bigger picture. Results may go up and down over time for different reasons, so careful interpretation is needed over the long term.
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Increased CA 27.29 levels are most associated with metastatic breast cancer, but they may also be caused by other conditions, including ovarian cysts and cancerous and noncancerous conditions of the kidney, breast and liver.
The CA 27.29 test is used for measuring how cancer is progressing and how the body is responding to treatment.
A CA 27.29 blood test looks for a specific type of tumor marker produced by the MUC1 gene. Elevated levels of this type of cancer antigen may be found in patients with metastatic breast cancer, meaning breast cancer that’s spread to distant areas of the body. For this reason, clinical guidelines recommend that tumor markers are used for metastatic breast cancer only and not for screening, diagnosing or monitoring localized breast cancer.
Other types of cancers and noncancerous conditions may show elevated 27.29 levels, which is why tumor marker tests are often used in combination with other tests.
While tumor markers like CA 27.29 have a strong association with metastatic breast cancer, these limitations are possible:
- CA 27.29 levels may not increase until after the cancer has advanced.
- Some patients with advanced cancers may not have increased levels, even though increased levels are likely.
- Both false negatives and false positives may occur.
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Unlimited Plan Member since 2021
I have been using Healthmatters.io since 2021. I travel all over the world and use different doctors and health facilities. This site has allowed me to consolidate all my various test results over 14 years in one place. And every doctor that I show this to has been impressed. Because with any health professional I talk to, I can pull up historical results in seconds. It is invaluable. Even going back to the same doctor, they usually do not have the historical results from their facility in a graph format. That has been very helpful.
Karin
Advanced Plan Member since 2020
What fantastic service and great, easy-to-follow layouts! I love your website; it makes it so helpful to see patterns in my health data. It's truly a pleasure to use. I only wish the NHS was as organized and quick as Healthmatters.io. You've set a new standard for health tracking!
Paul
Healthmatters Pro Member since 2024
As a PRO member and medical practitioner, Healthmatters.io has been an invaluable tool for tracking my clients' data. The layout is intuitive, making it easy to monitor trends and spot patterns over time. The ability to customize reports and charts helps me present information clearly to my clients, improving communication and outcomes. It's streamlined my workflow, saving me time and providing insights at a glance. Highly recommended for any practitioner looking for a comprehensive and user-friendly solution to track patient labs!
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Alpha Fetoprotein (AFP), CA 125, CA 15-3, CA 19-9, CA 27.29, CA 72-4, Carcinoembryonic Antigen (CEA), CD19, Chromogranin A (CgA), CYFRA 21-1 (Cytokeratin 19 Fragment), Leukemia/Lymphoma/Myeloma Panel by Flow Cytometry, Matrix Metalloproteinase 9 (MMP 9), MMP-9 (Matrix Metalloproteinase-9), Neuron-specific Enolase (NSE), Neurone Specific Enolase, PapIG, HPV, rfx 16/18, Prostate Cancer Risk Score, Prostate Specific Antigen (PSA), PSA, % Free, S100, Squamous Cell Carcinoma, Total Prostate Specific Antigen (TPSA), Urinary Bladder Cancer Antigen
