Genova: Amino Acids 40 Profile - Plasma

Phosphoethanolamine (Genova)

A healthy result should fall into the range 0 - 7.4 µmol/L.

Phosphoethanolamine together with Ethanolamine and Phosphoserine are amino acids that are closely related structurally and they share principal roles in phospholipid metabolism.

Phospholipids are a class of lipids that are important components of cell membranes. Phospholipids are found in high concentrations in the membrane of practically every cell of the body.

Phosphoethanolamine is a precursor to acetaldehyde, which can exert metabolic poisoning effects by irreversible binding to coenzyme A, especially in an individual with restricted intake of pantothenic acid (vitamin B5).

Mitochondrial inhibition by both ethanolaine and Phosphoethanolamine in vitro suggests that altered brain phospholipids metabolism may initiate depression and bipolar disorder.

Ethanolamine is converted to phosphoethanolamine via a magnesium- and manganese-dependent reaction.

References:

– https://www.sciencedirect.com/topics/medicine-and-dentistry/phosphoethanolamine

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