Haemoglobin A1c

Blood Health

A healthy result should fall into the range 0 - 0 %.

Hemoglobin A1c (HbA1c) is the percentage of hemoglobin molecules with attached glucose molecules. HbA1c is an accurate means to estimate the average blood glucose over the preceding 3 months. New hemoglobin molecules have very little attached glucose. Glucose becomes irreversibly attached to hemoglobin in proportion to the concentration of blood glucose. Since 1% of red blood cells are destroyed every day and replaced with an equal number, hemoglobin A1c is a dynamic way of measuring average blood glucose over the life the red blood cell. The average lifespan of red blood cell is 120 days thus hemoglobin A1c provides an accurate estimate of mean blood glucose over the previous 8 to 12 weeks. As such, hemoglobin A1c measurement does not require the person to fast prior to the test.

Normal Ranges for Hemoglobin A1c:

4.0-5.6%

<18 years: Hemoglobin A1c criteria for diagnosing diabetes have not been established for patients who are <18 years of age.

> or =18 years: Increased risk for diabetes (prediabetes): 5.7-6.4%

Diabetes: > or =6.5%

 

Sources:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3447844/

https://www.ncbi.nlm.nih.gov/pubmed/21584793

https://www.uptodate.com/contents/estimation-of-blood-glucose-control-in-diabetes-mellitus

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