A healthy result should fall into the range 0 - 0.22 Ratio.

Also known as: Alpha-Amino-N-Butyric Acid to Leucine ratio

Alcohol consumption can result in elevations of the plasma Alpha-ANB/Leucine ratio. But to see this biomarker as a conclusive marker for alcoholism is not proven. The increase in the plasma Alpha-ANB/Leucine ratio does not appear to be specific for alcoholism because it was found elevated in nonalcoholic liver disease.

It is most likely that the rise in the plasma Alpha-ANB/Leucine ratio identifies a subgroup of alcoholics. What determines this subgroup of alcoholics remains unclear, but it could be the quantity of alcohol intake, a nutritional deficiency, or the presence of liver disease.


  • Plasma alpha-amino-n-butyric acid/leucine ratio in alcoholics. (L)
  • On the clinical significance of the plasma alpha-amino-n-butyric acid:leucine ratio. (L)
  • Plasma alpha amino-n-butyric acid to leucine ratio: an empirical biochemical marker of alcoholism (L)
  • Ratio of plasma α-amino-n-butyric acid to leucine in alcoholism (L)

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